Metformin effects to carbohydrate and lipids metabolism in impaired glucose tolerance patients.

Aim of this study was to investigate the effect metformin to carbohydrate, lipids metabolism and leptin level in impaired glucose tolerance (IGT)patients.Methods. 16 patients with IGT were studied. Age of participant was 55.1?8.2 yrs. All patients was divide into two groups: treatment group (bagome...

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Bibliographic Details
Main Authors: Alexander Vasil'evich Dreval', Inna Vladimirovna Misnikova, Irina Vladimirovna Trigolosova, Raisa Stepanovna Tishenina
Format: Article
Language:English
Published: Endocrinology Research Centre 2010-06-01
Series:Сахарный диабет
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Online Access:https://www.dia-endojournals.ru/jour/article/view/5676
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Summary:Aim of this study was to investigate the effect metformin to carbohydrate, lipids metabolism and leptin level in impaired glucose tolerance (IGT)patients.Methods. 16 patients with IGT were studied. Age of participant was 55.1?8.2 yrs. All patients was divide into two groups: treatment group (bagomet1700 a day and diet) and control group (only diet). Effect of therapy was access in HbA1c, fasting glucose (FG), HOMA, lipids, liver glucose production(LGP) and leptin, which investigate in intravenous glucose tolerance test (IVGTT). Results. Normalization of carbohydrate metabolism was discover in 37.5% in treatment group and in 12.5% in control group. HbA1c was decreasefrom 6.4 to 5.9 % (р
ISSN:2072-0351
2072-0378