Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-Analysis
Blast mild traumatic brain injury (mTBI) is a unique injury in the military population and post-traumatic stress disorder (PTSD) is shown to be linked with it. The main purpose of the systematic review was to understand the impact of blast mTBI on PTSD symptom severity. We systematically searched Pu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Trauma Care |
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| Online Access: | https://www.mdpi.com/2673-866X/3/1/2 |
| _version_ | 1827747437281804288 |
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| author | Raphael Borinuoluwa Zubair Ahmed |
| author_facet | Raphael Borinuoluwa Zubair Ahmed |
| author_sort | Raphael Borinuoluwa |
| collection | DOAJ |
| description | Blast mild traumatic brain injury (mTBI) is a unique injury in the military population and post-traumatic stress disorder (PTSD) is shown to be linked with it. The main purpose of the systematic review was to understand the impact of blast mTBI on PTSD symptom severity. We systematically searched Pubmed, Web of Science, Embase (Ovid), APAPsycINFO (Ovid) and Medline (R) and In-Process, In-Data-Review and Other Non-Indexed Citations (Ovid). Data extraction and quality assessment was completed using the AXIS tool. Statistical analysis was undertaken to determine differences between blast mTBI and the control group (no blast and no TBI in military personnel) and a meta-analysis using the random effects model was used to calculate between-study heterogeneity and variance through I<sup>2</sup> and Tau<sup>2</sup>, respectively. Additionally, the likelihood of PTSD, analysed using the average PTSD Checklist (PCL) score, was also determined based. Statistically higher PCL scores were found in the blast mTBI group compared to control groups, but high heterogeneity was found between the studies (<i>p</i> < 0.001, I<sup>2</sup> = 84%, Tau<sup>2</sup> = 0.44). Furthermore, all studies reported that blast mTBI had probable PTSD, but this was not the case for the control group. Blast mTBI appears to impact on PTSD symptom severity and the likelihood of developing PTSD, which healthcare professionals need to be aware of. The high heterogeneity present in the studies means that caution must be exercised when interpreting the data from this study. However, future studies require more well-defined, high-quality studies to answer the question of how blast mTBI affects PTSD symptom severity. |
| first_indexed | 2024-03-11T05:49:34Z |
| format | Article |
| id | doaj.art-bfe4caa53f2a43d4baa94089f3316642 |
| institution | Directory Open Access Journal |
| issn | 2673-866X |
| language | English |
| last_indexed | 2024-03-11T05:49:34Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Trauma Care |
| spelling | doaj.art-bfe4caa53f2a43d4baa94089f33166422023-11-17T14:14:48ZengMDPI AGTrauma Care2673-866X2023-01-013192110.3390/traumacare3010002Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-AnalysisRaphael Borinuoluwa0Zubair Ahmed1Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKInstitute of Inflammation and Ageing, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKBlast mild traumatic brain injury (mTBI) is a unique injury in the military population and post-traumatic stress disorder (PTSD) is shown to be linked with it. The main purpose of the systematic review was to understand the impact of blast mTBI on PTSD symptom severity. We systematically searched Pubmed, Web of Science, Embase (Ovid), APAPsycINFO (Ovid) and Medline (R) and In-Process, In-Data-Review and Other Non-Indexed Citations (Ovid). Data extraction and quality assessment was completed using the AXIS tool. Statistical analysis was undertaken to determine differences between blast mTBI and the control group (no blast and no TBI in military personnel) and a meta-analysis using the random effects model was used to calculate between-study heterogeneity and variance through I<sup>2</sup> and Tau<sup>2</sup>, respectively. Additionally, the likelihood of PTSD, analysed using the average PTSD Checklist (PCL) score, was also determined based. Statistically higher PCL scores were found in the blast mTBI group compared to control groups, but high heterogeneity was found between the studies (<i>p</i> < 0.001, I<sup>2</sup> = 84%, Tau<sup>2</sup> = 0.44). Furthermore, all studies reported that blast mTBI had probable PTSD, but this was not the case for the control group. Blast mTBI appears to impact on PTSD symptom severity and the likelihood of developing PTSD, which healthcare professionals need to be aware of. The high heterogeneity present in the studies means that caution must be exercised when interpreting the data from this study. However, future studies require more well-defined, high-quality studies to answer the question of how blast mTBI affects PTSD symptom severity.https://www.mdpi.com/2673-866X/3/1/2blastmild traumatic brain injurypost-traumatic stress disorderblast injurymilitary personnel |
| spellingShingle | Raphael Borinuoluwa Zubair Ahmed Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-Analysis Trauma Care blast mild traumatic brain injury post-traumatic stress disorder blast injury military personnel |
| title | Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-Analysis |
| title_full | Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-Analysis |
| title_fullStr | Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-Analysis |
| title_short | Does Blast Mild Traumatic Brain Injury Have an Impact on PTSD Severity? A Systematic Review and Meta-Analysis |
| title_sort | does blast mild traumatic brain injury have an impact on ptsd severity a systematic review and meta analysis |
| topic | blast mild traumatic brain injury post-traumatic stress disorder blast injury military personnel |
| url | https://www.mdpi.com/2673-866X/3/1/2 |
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