Longitudinal long term follow up investigation on the carcinogenic impact of polyhexamethylene guanidine phosphate in rat models

Longitudinal long term follow up investigation on the carcinogenic impact of polyhexamethylene guanidine phosphate in rat models

Abstract Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated associations between PHMG-p dose and lung damage severity with long-term follow-up....

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Bibliographic Details
Main Authors: Sang Hoon Jeong, Hong Lee, Yoon Jeong Nam, Ja Young Kang, Hyejin Lee, Jin Young Choi, Yu-Seon Lee, Jaeyoung Kim, Yoon Hee Park, Su A. Park, Hangseok Choi, Eun-Kee Park, Yong-Wook Baek, Jungyun Lim, Suejin Kim, Cherry Kim, Ju-Han Lee
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Rat model
Polyhexamethylene guanidine phosphate
Chest CT
Lung cancer
Lung fibrosis
Online Access:https://doi.org/10.1038/s41598-024-57605-x

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