The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trial
Introduction: Sexual satisfaction is a person's positive evaluation of the sexual relationship. Decrease in sexual satisfaction is one of the common complaints of the postmenopausal period. Flaxseed is a phytoestrogen and contains lignan. The present study was conducted with aim to investigate...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | fas |
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Mashhad University of Medical Sciences
2023-06-01
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| Series: | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
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| Online Access: | https://ijogi.mums.ac.ir/article_22735_de6c11059cbe6b36f24de26d4d236ef3.pdf |
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| author | Fahimeh Shakeri Nahid Golmakani Seyed Reza Mazluom Shokouhsadat Hamedi Zohreh Feyzabadi Nafiseh Saghafi |
| author_facet | Fahimeh Shakeri Nahid Golmakani Seyed Reza Mazluom Shokouhsadat Hamedi Zohreh Feyzabadi Nafiseh Saghafi |
| author_sort | Fahimeh Shakeri |
| collection | DOAJ |
| description | Introduction: Sexual satisfaction is a person's positive evaluation of the sexual relationship. Decrease in sexual satisfaction is one of the common complaints of the postmenopausal period. Flaxseed is a phytoestrogen and contains lignan. The present study was conducted with aim to investigate the effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women.
Methods: This single-blind randomized clinical trial study was conducted in 2018-2019 on 60 married postmenopausal women aged 40 to 65 years referred to the clinics of Qaem and Imam Reza hospitals in Mashhad, Villa Shahr Health Center and the health center of Khalilabad city of Kashmar. The research units were randomly assigned in two groups of 30 people, vaginal cream of flaxseed and conjugated estrogen for 8 weeks. The intervention group received 4% vaginal gel in the form of one gram per day, and the flaxseed group received one gram per day for up to 8 weeks. Sexual satisfaction was calculated based on Larson's questionnaire before, 4 and 8 weeks after the study. Data analysis was done using SPSS statistical software (version 22) and Independent t-test, Friedman and Mann-Whitney tests. P<0.05 was considered statistically significant.Results: The mean sexual satisfaction 4 weeks after the intervention was 24.2 ± 10.4 in the flaxseed group and 23.4 ± 12.1 in the conjugated estrogen group (P=0.576), and after 8 weeks, it was 37.7 ± 18.2 in the flaxseed group and 37.8 ± 18.3 in the conjugated estrogen group, which did not show a significant difference between the two groups (P=0.638). Conclusion: Vaginal cream of flaxseed without any side effects compared to the side effects of hormone therapy can be as effective as conjugated estrogen vaginal cream in increasing sexual satisfaction. |
| first_indexed | 2024-03-12T23:17:41Z |
| format | Article |
| id | doaj.art-bfe91105208040de860539c1aa05d29d |
| institution | Directory Open Access Journal |
| issn | 1680-2993 2008-2363 |
| language | fas |
| last_indexed | 2024-03-12T23:17:41Z |
| publishDate | 2023-06-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
| spelling | doaj.art-bfe91105208040de860539c1aa05d29d2023-07-17T04:45:25ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632023-06-01264829110.22038/ijogi.2023.2273522735The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trialFahimeh Shakeri0Nahid Golmakani1Seyed Reza Mazluom2Shokouhsadat Hamedi3Zohreh Feyzabadi4Nafiseh Saghafi5M.Sc. of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Science, Mashhad, Iran.Assistant professor, Department of Midwifery, Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Instructor, Department of Nursing Education, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.Specialist in traditional medicine, School of Traditional and complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Assistant professor, Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.Associate professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: Sexual satisfaction is a person's positive evaluation of the sexual relationship. Decrease in sexual satisfaction is one of the common complaints of the postmenopausal period. Flaxseed is a phytoestrogen and contains lignan. The present study was conducted with aim to investigate the effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women. Methods: This single-blind randomized clinical trial study was conducted in 2018-2019 on 60 married postmenopausal women aged 40 to 65 years referred to the clinics of Qaem and Imam Reza hospitals in Mashhad, Villa Shahr Health Center and the health center of Khalilabad city of Kashmar. The research units were randomly assigned in two groups of 30 people, vaginal cream of flaxseed and conjugated estrogen for 8 weeks. The intervention group received 4% vaginal gel in the form of one gram per day, and the flaxseed group received one gram per day for up to 8 weeks. Sexual satisfaction was calculated based on Larson's questionnaire before, 4 and 8 weeks after the study. Data analysis was done using SPSS statistical software (version 22) and Independent t-test, Friedman and Mann-Whitney tests. P<0.05 was considered statistically significant.Results: The mean sexual satisfaction 4 weeks after the intervention was 24.2 ± 10.4 in the flaxseed group and 23.4 ± 12.1 in the conjugated estrogen group (P=0.576), and after 8 weeks, it was 37.7 ± 18.2 in the flaxseed group and 37.8 ± 18.3 in the conjugated estrogen group, which did not show a significant difference between the two groups (P=0.638). Conclusion: Vaginal cream of flaxseed without any side effects compared to the side effects of hormone therapy can be as effective as conjugated estrogen vaginal cream in increasing sexual satisfaction.https://ijogi.mums.ac.ir/article_22735_de6c11059cbe6b36f24de26d4d236ef3.pdfconjugated estrogenflaxseedmenopausesexual satisfactionvaginal cream |
| spellingShingle | Fahimeh Shakeri Nahid Golmakani Seyed Reza Mazluom Shokouhsadat Hamedi Zohreh Feyzabadi Nafiseh Saghafi The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trial Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān conjugated estrogen flaxseed menopause sexual satisfaction vaginal cream |
| title | The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trial |
| title_full | The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trial |
| title_fullStr | The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trial |
| title_full_unstemmed | The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trial |
| title_short | The effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women: A single-blind randomized clinical trial |
| title_sort | effect of vaginal cream of flaxseed and conjugated estrogen on sexual satisfaction in postmenopausal women a single blind randomized clinical trial |
| topic | conjugated estrogen flaxseed menopause sexual satisfaction vaginal cream |
| url | https://ijogi.mums.ac.ir/article_22735_de6c11059cbe6b36f24de26d4d236ef3.pdf |
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