Viscoelastic methods of blood clotting assessment – a multidisciplinary review

Viscoelastic methods made available the bed-side assessment of blood clotting. Unlike standard laboratory tests, the results are based on the whole blood coagulation, are available in real time and in much faster turnaround time. In combination with our new knowledge about pathophysiology of the tra...

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Main Authors: Jan eBenes, Jan eZatloukal, Jakub eKletecka
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00062/full
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author Jan eBenes
Jan eBenes
Jan eZatloukal
Jakub eKletecka
author_facet Jan eBenes
Jan eBenes
Jan eZatloukal
Jakub eKletecka
author_sort Jan eBenes
collection DOAJ
description Viscoelastic methods made available the bed-side assessment of blood clotting. Unlike standard laboratory tests, the results are based on the whole blood coagulation, are available in real time and in much faster turnaround time. In combination with our new knowledge about pathophysiology of the trauma induced coagulopathy the goal oriented treatment protocols have been recently proposed for the initial management of bleeding in trauma victims. Besides, the utility of viscoelastic monitoring devices has been proved even outside this setting in cardiosurgical patients or those undergoing liver transplantation. Many other situations were described in literature showing potential use of bed-side analysis of coagulation for the management of bleeding or critically ill patients. In the near future, we may expect further improvement of current bed-side diagnostic tools enabling not only the assessment of secondary hemostasis but also platelet aggregation. More sensitive assays for new anticoagulants are underway. Aim of this review is to offer the reader a multidisciplinary overview on the topic of viscoelastic methods and their potential use in anesthesiology and critical care.
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spelling doaj.art-bfead20491b34215a9324863dc3dec812022-12-21T23:23:50ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2015-09-01210.3389/fmed.2015.00062151748Viscoelastic methods of blood clotting assessment – a multidisciplinary reviewJan eBenes0Jan eBenes1Jan eZatloukal2Jakub eKletecka3Faculty of Medicine and Teaching hospital in Plzen, Charles University in PragueFaculty of Medicine in Plzen, Charles University in PragueFaculty of Medicine and Teaching hospital in Plzen, Charles University in PragueFaculty of Medicine and Teaching hospital in Plzen, Charles University in PragueViscoelastic methods made available the bed-side assessment of blood clotting. Unlike standard laboratory tests, the results are based on the whole blood coagulation, are available in real time and in much faster turnaround time. In combination with our new knowledge about pathophysiology of the trauma induced coagulopathy the goal oriented treatment protocols have been recently proposed for the initial management of bleeding in trauma victims. Besides, the utility of viscoelastic monitoring devices has been proved even outside this setting in cardiosurgical patients or those undergoing liver transplantation. Many other situations were described in literature showing potential use of bed-side analysis of coagulation for the management of bleeding or critically ill patients. In the near future, we may expect further improvement of current bed-side diagnostic tools enabling not only the assessment of secondary hemostasis but also platelet aggregation. More sensitive assays for new anticoagulants are underway. Aim of this review is to offer the reader a multidisciplinary overview on the topic of viscoelastic methods and their potential use in anesthesiology and critical care.http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00062/fullThrombosiscoagulationtransfusionPoint-of care testingtrauma induced coagulopathyviscoelastic methods
spellingShingle Jan eBenes
Jan eBenes
Jan eZatloukal
Jakub eKletecka
Viscoelastic methods of blood clotting assessment – a multidisciplinary review
Frontiers in Medicine
Thrombosis
coagulation
transfusion
Point-of care testing
trauma induced coagulopathy
viscoelastic methods
title Viscoelastic methods of blood clotting assessment – a multidisciplinary review
title_full Viscoelastic methods of blood clotting assessment – a multidisciplinary review
title_fullStr Viscoelastic methods of blood clotting assessment – a multidisciplinary review
title_full_unstemmed Viscoelastic methods of blood clotting assessment – a multidisciplinary review
title_short Viscoelastic methods of blood clotting assessment – a multidisciplinary review
title_sort viscoelastic methods of blood clotting assessment a multidisciplinary review
topic Thrombosis
coagulation
transfusion
Point-of care testing
trauma induced coagulopathy
viscoelastic methods
url http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00062/full
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AT jakubekletecka viscoelasticmethodsofbloodclottingassessmentamultidisciplinaryreview