Phosphorylation of ERK-Dependent NF-κB Triggers NLRP3 Inflammasome Mediated by Vimentin in EV71-Infected Glioblastoma Cells

Phosphorylation of ERK-Dependent NF-κB Triggers NLRP3 Inflammasome Mediated by Vimentin in EV71-Infected Glioblastoma Cells

Enterovirus 71 (EV71) is a dominant pathogenic agent that may cause severe central nervous system (CNS) diseases among infants and young children in the Asia-pacific. The inflammasome is closely implicated in EV71-induced CNS injuries through a series of signaling pathways. However, the activation p...

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Bibliographic Details
Main Authors: Zelong Gong, Xuefeng Gao, Qingqing Yang, Jingxian Lun, Hansen Xiao, Jiayu Zhong, Hong Cao
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
enterovirus 71
phosphorylation of ERK1/2
NLRP3
vimentin
NF-κB
glioblastoma cells
Online Access:https://www.mdpi.com/1420-3049/27/13/4190

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https://www.mdpi.com/1420-3049/27/13/4190

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