Epidural fibrosis after lumbar spinal surgery

The surgical treatment of the lumbar disc hernia is, in same cases, followed by complications which are included in a clinical syndrome named failed back surgery syndrome (FBSS). Lumbar fibrosis is responsible in 24% of cases of FBSS. We review the literature concerning this subject. Many studies lo...

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Bibliographic Details
Main Authors: Danil Adam, Cristina Adam, Ioana Hornea
Format: Article
Language:English
Published: London Academic Publishing 2007-08-01
Series:Romanian Neurosurgery
Subjects:
Online Access:https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/396
Description
Summary:The surgical treatment of the lumbar disc hernia is, in same cases, followed by complications which are included in a clinical syndrome named failed back surgery syndrome (FBSS). Lumbar fibrosis is responsible in 24% of cases of FBSS. We review the literature concerning this subject. Many studies looked for methods to prevent this complication, with moderate effectiveness. ADCON gel, which raised great expectations - produced no positive effect in patients who underwent microdiscectomy, and is now out of use. Currently, the results of experimental studies with local Mitomycin C and preoperative extenal radiotherapy (7 Gy) are promising and allow us performing clinical studies.
ISSN:1220-8841
2344-4959