Epidural fibrosis after lumbar spinal surgery
The surgical treatment of the lumbar disc hernia is, in same cases, followed by complications which are included in a clinical syndrome named failed back surgery syndrome (FBSS). Lumbar fibrosis is responsible in 24% of cases of FBSS. We review the literature concerning this subject. Many studies lo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
London Academic Publishing
2007-08-01
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| Series: | Romanian Neurosurgery |
| Subjects: | |
| Online Access: | https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/396 |
| _version_ | 1817993649750802432 |
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| author | Danil Adam Cristina Adam Ioana Hornea |
| author_facet | Danil Adam Cristina Adam Ioana Hornea |
| author_sort | Danil Adam |
| collection | DOAJ |
| description | The surgical treatment of the lumbar disc hernia is, in same cases, followed by complications which are included in a clinical syndrome named failed back surgery syndrome (FBSS). Lumbar fibrosis is responsible in 24% of cases of FBSS. We review the literature concerning this subject. Many studies looked for methods to prevent this complication, with moderate effectiveness. ADCON gel, which raised great expectations - produced no positive effect in patients who underwent microdiscectomy, and is now out of use. Currently, the results of experimental studies with local Mitomycin C and preoperative extenal radiotherapy (7 Gy) are promising and allow us performing clinical studies. |
| first_indexed | 2024-04-14T01:42:35Z |
| format | Article |
| id | doaj.art-bfebc32c741c4de3bf675bf5ee40c1e2 |
| institution | Directory Open Access Journal |
| issn | 1220-8841 2344-4959 |
| language | English |
| last_indexed | 2024-04-14T01:42:35Z |
| publishDate | 2007-08-01 |
| publisher | London Academic Publishing |
| record_format | Article |
| series | Romanian Neurosurgery |
| spelling | doaj.art-bfebc32c741c4de3bf675bf5ee40c1e22022-12-22T02:19:41ZengLondon Academic PublishingRomanian Neurosurgery1220-88412344-49592007-08-01142Epidural fibrosis after lumbar spinal surgeryDanil AdamCristina AdamIoana HorneaThe surgical treatment of the lumbar disc hernia is, in same cases, followed by complications which are included in a clinical syndrome named failed back surgery syndrome (FBSS). Lumbar fibrosis is responsible in 24% of cases of FBSS. We review the literature concerning this subject. Many studies looked for methods to prevent this complication, with moderate effectiveness. ADCON gel, which raised great expectations - produced no positive effect in patients who underwent microdiscectomy, and is now out of use. Currently, the results of experimental studies with local Mitomycin C and preoperative extenal radiotherapy (7 Gy) are promising and allow us performing clinical studies.https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/396peridural fibrosisradiotherapyMitomycin C |
| spellingShingle | Danil Adam Cristina Adam Ioana Hornea Epidural fibrosis after lumbar spinal surgery Romanian Neurosurgery peridural fibrosis radiotherapy Mitomycin C |
| title | Epidural fibrosis after lumbar spinal surgery |
| title_full | Epidural fibrosis after lumbar spinal surgery |
| title_fullStr | Epidural fibrosis after lumbar spinal surgery |
| title_full_unstemmed | Epidural fibrosis after lumbar spinal surgery |
| title_short | Epidural fibrosis after lumbar spinal surgery |
| title_sort | epidural fibrosis after lumbar spinal surgery |
| topic | peridural fibrosis radiotherapy Mitomycin C |
| url | https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/396 |
| work_keys_str_mv | AT daniladam epiduralfibrosisafterlumbarspinalsurgery AT cristinaadam epiduralfibrosisafterlumbarspinalsurgery AT ioanahornea epiduralfibrosisafterlumbarspinalsurgery |