Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study
Background: Surgical site infection (SSI) is one of the common postoperative complications observed after various periodontal surgeries, and sutures play a vital role in its causation. Thus, the aim of this study is to evaluate and compare the efficacy of a novel tetracycline-coated suture with tric...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Indian Society of Periodontology |
| Subjects: | |
| Online Access: | http://www.jisponline.com/article.asp?issn=0972-124X;year=2022;volume=26;issue=6;spage=539;epage=543;aulast=Banodkar |
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| author | Akshaya Bhupesh Banodkar Vaibhavi Pandurang Nandgaonkar Rajesh Prabhakar Gaikwad Lynette Custodio Fernandes Chitra Laxmikant Patil Amrita Dharmendra Batho |
| author_facet | Akshaya Bhupesh Banodkar Vaibhavi Pandurang Nandgaonkar Rajesh Prabhakar Gaikwad Lynette Custodio Fernandes Chitra Laxmikant Patil Amrita Dharmendra Batho |
| author_sort | Akshaya Bhupesh Banodkar |
| collection | DOAJ |
| description | Background: Surgical site infection (SSI) is one of the common postoperative complications observed after various periodontal surgeries, and sutures play a vital role in its causation. Thus, the aim of this study is to evaluate and compare the efficacy of a novel tetracycline-coated suture with triclosan-coated and nonantibacterial-coated sutures on bacterial load reduction to prevent SSI by measuring the zone of inhibition. Materials and Methods: Twenty systemically healthy individuals with moderate chronic periodontitis were included in this study. Fresh unstimulated saliva was collected from each patient and inoculated on three different blood agar plates. Sutures were divided into three groups (Group A: Tetracycline-coated suture, Group B: Triclosan-coated suture, Group C [control group]: Nonantibacterial-coated suture). The antibacterial efficacy of each suture was evaluated by performing agar diffusion test. The zone of inhibition around each suture was calculated, and statistical analysis was performed for the same using Kruskall–Wallis ANOVA test and Mann–Whitney U-test. Results: On intergroup comparison, there was a statistically highly significant difference seen for the zone of inhibition between the groups (P < 0.01) with the highest values in Group A (14.45 mm), followed by Group B (1.4 mm) and least in Group C (0 mm). Conclusion: Tetracycline-coated suture is more efficacious than triclosan-coated suture to reduce bacterial load and further prevent SSIs. However, in vivo clinical trial is must to prove the same. |
| first_indexed | 2024-04-12T01:55:09Z |
| format | Article |
| id | doaj.art-bfed28135e7b455a89f226d6aa3bf32d |
| institution | Directory Open Access Journal |
| issn | 0972-124X |
| language | English |
| last_indexed | 2024-04-12T01:55:09Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Periodontology |
| spelling | doaj.art-bfed28135e7b455a89f226d6aa3bf32d2022-12-22T03:52:50ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2022-01-0126653954310.4103/jisp.jisp_453_21Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro studyAkshaya Bhupesh BanodkarVaibhavi Pandurang NandgaonkarRajesh Prabhakar GaikwadLynette Custodio FernandesChitra Laxmikant PatilAmrita Dharmendra BathoBackground: Surgical site infection (SSI) is one of the common postoperative complications observed after various periodontal surgeries, and sutures play a vital role in its causation. Thus, the aim of this study is to evaluate and compare the efficacy of a novel tetracycline-coated suture with triclosan-coated and nonantibacterial-coated sutures on bacterial load reduction to prevent SSI by measuring the zone of inhibition. Materials and Methods: Twenty systemically healthy individuals with moderate chronic periodontitis were included in this study. Fresh unstimulated saliva was collected from each patient and inoculated on three different blood agar plates. Sutures were divided into three groups (Group A: Tetracycline-coated suture, Group B: Triclosan-coated suture, Group C [control group]: Nonantibacterial-coated suture). The antibacterial efficacy of each suture was evaluated by performing agar diffusion test. The zone of inhibition around each suture was calculated, and statistical analysis was performed for the same using Kruskall–Wallis ANOVA test and Mann–Whitney U-test. Results: On intergroup comparison, there was a statistically highly significant difference seen for the zone of inhibition between the groups (P < 0.01) with the highest values in Group A (14.45 mm), followed by Group B (1.4 mm) and least in Group C (0 mm). Conclusion: Tetracycline-coated suture is more efficacious than triclosan-coated suture to reduce bacterial load and further prevent SSIs. However, in vivo clinical trial is must to prove the same.http://www.jisponline.com/article.asp?issn=0972-124X;year=2022;volume=26;issue=6;spage=539;epage=543;aulast=Banodkaragar diffusion testsurgical site infectionsuturetetracycline-coated suturetriclosan-coated suturezone of inhibition |
| spellingShingle | Akshaya Bhupesh Banodkar Vaibhavi Pandurang Nandgaonkar Rajesh Prabhakar Gaikwad Lynette Custodio Fernandes Chitra Laxmikant Patil Amrita Dharmendra Batho Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study Journal of Indian Society of Periodontology agar diffusion test surgical site infection suture tetracycline-coated suture triclosan-coated suture zone of inhibition |
| title | Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study |
| title_full | Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study |
| title_fullStr | Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study |
| title_full_unstemmed | Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study |
| title_short | Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study |
| title_sort | comparative evaluation of the efficacy of a novel tetracycline coated suture with triclosan coated and noncoated sutures on bacterial load reduction a prospective in vitro study |
| topic | agar diffusion test surgical site infection suture tetracycline-coated suture triclosan-coated suture zone of inhibition |
| url | http://www.jisponline.com/article.asp?issn=0972-124X;year=2022;volume=26;issue=6;spage=539;epage=543;aulast=Banodkar |
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