The state of erythrocyte membranes in newborn infants born to mothers with gestosis

Objective: to study the specific structural and functional features of erythrocyte membranes in the neonatal infants (и=181) from mothers with gestosis in relation to the clinical course of an early postnatal adaptation process. A control group consisted of 42 neo-nates rom mothers with physiologica...

Full description

Bibliographic Details
Main Authors: V. T. Manchuk, M. V. Shubina, Ya. Kh. Davaa, S. Yu. Tereshchenko
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2016-03-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/234
_version_ 1797875330898198528
author V. T. Manchuk
M. V. Shubina
Ya. Kh. Davaa
S. Yu. Tereshchenko
author_facet V. T. Manchuk
M. V. Shubina
Ya. Kh. Davaa
S. Yu. Tereshchenko
author_sort V. T. Manchuk
collection DOAJ
description Objective: to study the specific structural and functional features of erythrocyte membranes in the neonatal infants (и=181) from mothers with gestosis in relation to the clinical course of an early postnatal adaptation process. A control group consisted of 42 neo-nates rom mothers with physiological pregnancy. The biophysical state of erythrocyte membranes was investigated by fluorescence spectroscopy at birth and on day 4 of life. The indicators of fluidity in the deep and paraprotein layers of phospholipids were determined in relation to the pyrene eximer-to-monomer fluorescence ratio. By day 4 of life, the neonatal infants of healthy mothers were found to have increased viscosity (decreased fluidity) of membranes, which may be considered as an adaptive compensation mechanism upon transition to new living conditions. In the neonates of mothers with gestosis, these membrane changes were less pronounced and those of mothers with severe gestosis had no significant increase in membrane viscosity by day 4 of life, which was associated with the more severe course of an early postnatal adaptation period.
first_indexed 2024-04-10T01:44:53Z
format Article
id doaj.art-bff1407d00434d2a87a84e475ffde20f
institution Directory Open Access Journal
issn 1027-4065
2500-2228
language Russian
last_indexed 2024-04-10T01:44:53Z
publishDate 2016-03-01
publisher Ltd. “The National Academy of Pediatric Science and Innovation”
record_format Article
series Rossijskij Vestnik Perinatologii i Pediatrii
spelling doaj.art-bff1407d00434d2a87a84e475ffde20f2023-03-13T09:12:41ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282016-03-015954546227The state of erythrocyte membranes in newborn infants born to mothers with gestosisV. T. Manchuk0M. V. Shubina1Ya. Kh. Davaa2S. Yu. Tereshchenko3НИИ медицинских проблем Севера СО РАМН, КрасноярскНИИ медицинских проблем Севера СО РАМН, КрасноярскНИИ медицинских проблем Севера СО РАМН, КрасноярскНИИ медицинских проблем Севера СО РАМН, КрасноярскObjective: to study the specific structural and functional features of erythrocyte membranes in the neonatal infants (и=181) from mothers with gestosis in relation to the clinical course of an early postnatal adaptation process. A control group consisted of 42 neo-nates rom mothers with physiological pregnancy. The biophysical state of erythrocyte membranes was investigated by fluorescence spectroscopy at birth and on day 4 of life. The indicators of fluidity in the deep and paraprotein layers of phospholipids were determined in relation to the pyrene eximer-to-monomer fluorescence ratio. By day 4 of life, the neonatal infants of healthy mothers were found to have increased viscosity (decreased fluidity) of membranes, which may be considered as an adaptive compensation mechanism upon transition to new living conditions. In the neonates of mothers with gestosis, these membrane changes were less pronounced and those of mothers with severe gestosis had no significant increase in membrane viscosity by day 4 of life, which was associated with the more severe course of an early postnatal adaptation period.https://www.ped-perinatology.ru/jour/article/view/234новорожденныегестозпроцесс адаптацииэритроцитарные мембраны
spellingShingle V. T. Manchuk
M. V. Shubina
Ya. Kh. Davaa
S. Yu. Tereshchenko
The state of erythrocyte membranes in newborn infants born to mothers with gestosis
Rossijskij Vestnik Perinatologii i Pediatrii
новорожденные
гестоз
процесс адаптации
эритроцитарные мембраны
title The state of erythrocyte membranes in newborn infants born to mothers with gestosis
title_full The state of erythrocyte membranes in newborn infants born to mothers with gestosis
title_fullStr The state of erythrocyte membranes in newborn infants born to mothers with gestosis
title_full_unstemmed The state of erythrocyte membranes in newborn infants born to mothers with gestosis
title_short The state of erythrocyte membranes in newborn infants born to mothers with gestosis
title_sort state of erythrocyte membranes in newborn infants born to mothers with gestosis
topic новорожденные
гестоз
процесс адаптации
эритроцитарные мембраны
url https://www.ped-perinatology.ru/jour/article/view/234
work_keys_str_mv AT vtmanchuk thestateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis
AT mvshubina thestateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis
AT yakhdavaa thestateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis
AT syutereshchenko thestateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis
AT vtmanchuk stateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis
AT mvshubina stateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis
AT yakhdavaa stateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis
AT syutereshchenko stateoferythrocytemembranesinnewborninfantsborntomotherswithgestosis