Sensor Histidine Kinase NarQ Activates via Helical Rotation, Diagonal Scissoring, and Eventually Piston-Like Shifts

Sensor Histidine Kinase NarQ Activates via Helical Rotation, Diagonal Scissoring, and Eventually Piston-Like Shifts

Membrane-embedded sensor histidine kinases (HKs) and chemoreceptors are used ubiquitously by bacteria and archaea to percept the environment, and are often crucial for their survival and pathogenicity. The proteins can transmit the signal from the sensor domain to the catalytic kinase domain reliabl...

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Bibliographic Details
Main Authors: Ivan Gushchin, Philipp Orekhov, Igor Melnikov, Vitaly Polovinkin, Anastasia Yuzhakova, Valentin Gordeliy
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
two-component systems
histidine kinase
receptor
transmembrane signaling
X-ray crystallography
molecular dynamics
Online Access:https://www.mdpi.com/1422-0067/21/9/3110

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