Heart Rate–Induced Myocardial Ca2+ Retention and Left Ventricular Volume Loss in Patients With Heart Failure With Preserved Ejection Fraction

Heart Rate–Induced Myocardial Ca2+ Retention and Left Ventricular Volume Loss in Patients With Heart Failure With Preserved Ejection Fraction

Background Increases in heart rate are thought to result in incomplete left ventricular (LV) relaxation and elevated filling pressures in patients with heart failure with preserved ejection fraction (HFpEF). Experimental studies in isolated human myocardium have suggested that incomplete relaxation...

Full description

Bibliographic Details
Main Authors: Daniel N. Silverman, Mehdi Rambod, Daniel L. Lustgarten, Robert Lobel, Martin M. LeWinter, Markus Meyer
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Ca2+ cycling/excitation-contraction coupling
heart failure
hypertension
ion channels/membrane transport
mechanisms
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.017215

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.017215

Similar Items