Obesity Promotes Cooperation of Cancer Stem-Like Cells and Macrophages to Enhance Mammary Tumor Angiogenesis

Obesity is correlated with worsened prognosis and treatment resistance in breast cancer. Macrophage-targeted therapies are currently in clinical trials, however, little is known about how obesity may impact treatment efficacy. Within breast adipose tissue, obesity leads to chronic, macrophage-driven...

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Bibliographic Details
Main Authors: Lauren E. Hillers-Ziemer, Rachel Q. McMahon, Margaret Hietpas, Gretchen Paderta, Jennelle LeBeau, Jessica McCready, Lisa M. Arendt
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/2/502