Severe cytokine release syndrome induced by immune checkpoint inhibitors in cancer patients – A case report and review of the literature

Severe cytokine release syndrome induced by immune checkpoint inhibitors in cancer patients – A case report and review of the literature

Cytokine release syndrome (CRS) can be induced by immune checkpoint inhibitors (ICIs). Although the incidence of CRS is low, it is often underreported. Here, we report two severe CRS cases and summarize and review 51 patients with ICI-induced CRS to explore the possible contributing factors to the d...

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Bibliographic Details
Main Authors: Yujing Zhang, Xiaoyue Wen, Yaqi OuYang, Yingying Hu, Xiangzhi Fang, Jiancheng Zhang, Yin Yuan
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Immunotherapy
Immune checkpoint inhibitor
Immune-related adverse event
Cytokine release syndrome
Case report
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024004110

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