Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes.
Grapes are rich in phytochemicals with many proven health benefits. Phenolic profiles, antioxidant and antiproliferative activities of twenty-four selected Vitis vinifera grape cultivars were investigated in this study. Large ranges of variation were found in these cultivars for the contents of tota...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4136860?pdf=render |
| _version_ | 1818035148319358976 |
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| author | Zhenchang Liang Lailiang Cheng Gan-Yuan Zhong Rui Hai Liu |
| author_facet | Zhenchang Liang Lailiang Cheng Gan-Yuan Zhong Rui Hai Liu |
| author_sort | Zhenchang Liang |
| collection | DOAJ |
| description | Grapes are rich in phytochemicals with many proven health benefits. Phenolic profiles, antioxidant and antiproliferative activities of twenty-four selected Vitis vinifera grape cultivars were investigated in this study. Large ranges of variation were found in these cultivars for the contents of total phenolics (95.3 to 686.5 mg/100 g) and flavonoids (94.7 to 1055 mg/100 g) and antioxidant activities (oxygen radical absorbance capacity 378.7 to 3386.0 mg of Trolox equivalents/100 g and peroxylradical scavenging capacity14.2 to 557 mg of vitamin C equivalents/100 g), cellular antioxidant activities (3.9 to 139.9 µmol of quercetin equivalents/100 g without PBS wash and 1.4 to 95.8 µmol of quercetin equivalents /100 g with PBS wash) and antiproliferative activities (25 to 82% at the concentrations of 100 mg/mL extracts).The total antioxidant activities were significantly correlated with the total phenolics and flavonoids. However, no significant correlations were found between antiproliferative activities and total phenolics or total flavonoids content. Wine grapes and color grapes showed much higher levels of phytochemicals and antioxidant activities than table grapes and green/yellow grapes. Several germplasm accessions with much high contents of phenolics and flavonoids, and total antioxidant activity were identified. These germplasm can be valuable sources of genes for breeding grape cultivars with better nutritional qualities of wine and table grapes in the future. |
| first_indexed | 2024-12-10T06:50:27Z |
| format | Article |
| id | doaj.art-c008e7aca03f4d2c81826a4efe18c3e3 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-10T06:50:27Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c008e7aca03f4d2c81826a4efe18c3e32022-12-22T01:58:34ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0198e10514610.1371/journal.pone.0105146Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes.Zhenchang LiangLailiang ChengGan-Yuan ZhongRui Hai LiuGrapes are rich in phytochemicals with many proven health benefits. Phenolic profiles, antioxidant and antiproliferative activities of twenty-four selected Vitis vinifera grape cultivars were investigated in this study. Large ranges of variation were found in these cultivars for the contents of total phenolics (95.3 to 686.5 mg/100 g) and flavonoids (94.7 to 1055 mg/100 g) and antioxidant activities (oxygen radical absorbance capacity 378.7 to 3386.0 mg of Trolox equivalents/100 g and peroxylradical scavenging capacity14.2 to 557 mg of vitamin C equivalents/100 g), cellular antioxidant activities (3.9 to 139.9 µmol of quercetin equivalents/100 g without PBS wash and 1.4 to 95.8 µmol of quercetin equivalents /100 g with PBS wash) and antiproliferative activities (25 to 82% at the concentrations of 100 mg/mL extracts).The total antioxidant activities were significantly correlated with the total phenolics and flavonoids. However, no significant correlations were found between antiproliferative activities and total phenolics or total flavonoids content. Wine grapes and color grapes showed much higher levels of phytochemicals and antioxidant activities than table grapes and green/yellow grapes. Several germplasm accessions with much high contents of phenolics and flavonoids, and total antioxidant activity were identified. These germplasm can be valuable sources of genes for breeding grape cultivars with better nutritional qualities of wine and table grapes in the future.http://europepmc.org/articles/PMC4136860?pdf=render |
| spellingShingle | Zhenchang Liang Lailiang Cheng Gan-Yuan Zhong Rui Hai Liu Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes. PLoS ONE |
| title | Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes. |
| title_full | Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes. |
| title_fullStr | Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes. |
| title_full_unstemmed | Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes. |
| title_short | Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes. |
| title_sort | antioxidant and antiproliferative activities of twenty four vitis vinifera grapes |
| url | http://europepmc.org/articles/PMC4136860?pdf=render |
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