Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts
Alcohol craving can be enhanced by alcohol-associated cues and by alcohol-associated contexts. Here the authors investigate the role of the ventral tegmental area (VTA)-to-nucleus accumbens (NAc) core and VTA-to-NAc shell circuits in mediating these distinct aspects of alcohol seeking behaviour in r...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-17543-4 |
| _version_ | 1818422319729606656 |
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| author | Milan D. Valyear Iulia Glovaci Audrey Zaari Soraya Lahlou Ivan Trujillo-Pisanty C. Andrew Chapman Nadia Chaudhri |
| author_facet | Milan D. Valyear Iulia Glovaci Audrey Zaari Soraya Lahlou Ivan Trujillo-Pisanty C. Andrew Chapman Nadia Chaudhri |
| author_sort | Milan D. Valyear |
| collection | DOAJ |
| description | Alcohol craving can be enhanced by alcohol-associated cues and by alcohol-associated contexts. Here the authors investigate the role of the ventral tegmental area (VTA)-to-nucleus accumbens (NAc) core and VTA-to-NAc shell circuits in mediating these distinct aspects of alcohol seeking behaviour in rats. |
| first_indexed | 2024-12-14T13:24:22Z |
| format | Article |
| id | doaj.art-c0094cdd4a5e4906911650082447d0bd |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T13:24:22Z |
| publishDate | 2020-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-c0094cdd4a5e4906911650082447d0bd2022-12-21T22:59:51ZengNature PortfolioNature Communications2041-17232020-07-0111111410.1038/s41467-020-17543-4Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contextsMilan D. Valyear0Iulia Glovaci1Audrey Zaari2Soraya Lahlou3Ivan Trujillo-Pisanty4C. Andrew Chapman5Nadia Chaudhri6Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia UniversityCenter for Studies in Behavioral Neurobiology, Department of Psychology, Concordia UniversityCenter for Studies in Behavioral Neurobiology, Department of Psychology, Concordia UniversityCenter for Studies in Behavioral Neurobiology, Department of Psychology, Concordia UniversityCenter for Studies in Behavioral Neurobiology, Department of Psychology, Concordia UniversityCenter for Studies in Behavioral Neurobiology, Department of Psychology, Concordia UniversityCenter for Studies in Behavioral Neurobiology, Department of Psychology, Concordia UniversityAlcohol craving can be enhanced by alcohol-associated cues and by alcohol-associated contexts. Here the authors investigate the role of the ventral tegmental area (VTA)-to-nucleus accumbens (NAc) core and VTA-to-NAc shell circuits in mediating these distinct aspects of alcohol seeking behaviour in rats.https://doi.org/10.1038/s41467-020-17543-4 |
| spellingShingle | Milan D. Valyear Iulia Glovaci Audrey Zaari Soraya Lahlou Ivan Trujillo-Pisanty C. Andrew Chapman Nadia Chaudhri Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts Nature Communications |
| title | Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts |
| title_full | Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts |
| title_fullStr | Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts |
| title_full_unstemmed | Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts |
| title_short | Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts |
| title_sort | dissociable mesolimbic dopamine circuits control responding triggered by alcohol predictive discrete cues and contexts |
| url | https://doi.org/10.1038/s41467-020-17543-4 |
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