Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization
Objective: To investigate the hemodynamic features before and after embolization of paraclinoidal aneurysms using hemodynamic numerical simulation and the influence of embolization on recurrence after embolization.Methods: From January 2016 to December 2017, we enrolled a total of 113 paraclinoidal...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-04-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2019.00429/full |
| _version_ | 1811240096059359232 |
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| author | Bin Sheng Degang Wu Jinlong Yuan Shanshui Xu Zhenbao Li Jin Dong Niansheng Lai Xinggen Fang |
| author_facet | Bin Sheng Degang Wu Jinlong Yuan Shanshui Xu Zhenbao Li Jin Dong Niansheng Lai Xinggen Fang |
| author_sort | Bin Sheng |
| collection | DOAJ |
| description | Objective: To investigate the hemodynamic features before and after embolization of paraclinoidal aneurysms using hemodynamic numerical simulation and the influence of embolization on recurrence after embolization.Methods: From January 2016 to December 2017, we enrolled a total of 113 paraclinoidal aneurysms treated with embolization. They were divided into recurrent group and stable group depending on follow-up results. An aneurysm model was generated based on 3D-DSA before and after embolization. The hemodynamic characteristics were analyzed between two groups using Computational fluid dynamic (CFD).Results: In the recurrent group, the peak systolic WSS, OSI and velocity around the aneurysm neck areas prior to embolization were 20.47 ± 3.04 Pa, 0.06 ± 0.02 and 0.07 ± 0.03 m/s, respectively. These values were 23.50 ± 4.11 Pa, 0.06 ± 0.01 and 0.11 ± 0.02 m/s, respectively in the stable group (P > 0.05). The WSS, OSI, velocity around the same areas in the recurrent group after embolization were 35.59 ± 8.75 Pa, 0.07 ± 0.02 and 0.12 ± 0.03 m/s, respectively (P < 0.01). In the stable group, the WSS, OSI and velocity were 13.08 ± 2.89 Pa, 0.04 ± 0.01 and 0.07 ± 0.02 m/s, respectively (P < 0.01). After embolization, the WSS, OSI and velocity around the aneurysm neck areas in the recurrent group were significantly higher than those in the stable group.Conclusions: High peak systolic WSS, OSI and velocity around aneurysm neck areas after embolization of paraclinoidal aneurysms may be important factors leading to recurrence. |
| first_indexed | 2024-04-12T13:13:13Z |
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| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-12T13:13:13Z |
| publishDate | 2019-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-c009abb6aac24fa1a9a495490957641d2022-12-22T03:31:47ZengFrontiers Media S.A.Frontiers in Neurology1664-22952019-04-011010.3389/fneur.2019.00429432790Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After EmbolizationBin Sheng0Degang Wu1Jinlong Yuan2Shanshui Xu3Zhenbao Li4Jin Dong5Niansheng Lai6Xinggen Fang7Department of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaDepartment of Nursing, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, ChinaObjective: To investigate the hemodynamic features before and after embolization of paraclinoidal aneurysms using hemodynamic numerical simulation and the influence of embolization on recurrence after embolization.Methods: From January 2016 to December 2017, we enrolled a total of 113 paraclinoidal aneurysms treated with embolization. They were divided into recurrent group and stable group depending on follow-up results. An aneurysm model was generated based on 3D-DSA before and after embolization. The hemodynamic characteristics were analyzed between two groups using Computational fluid dynamic (CFD).Results: In the recurrent group, the peak systolic WSS, OSI and velocity around the aneurysm neck areas prior to embolization were 20.47 ± 3.04 Pa, 0.06 ± 0.02 and 0.07 ± 0.03 m/s, respectively. These values were 23.50 ± 4.11 Pa, 0.06 ± 0.01 and 0.11 ± 0.02 m/s, respectively in the stable group (P > 0.05). The WSS, OSI, velocity around the same areas in the recurrent group after embolization were 35.59 ± 8.75 Pa, 0.07 ± 0.02 and 0.12 ± 0.03 m/s, respectively (P < 0.01). In the stable group, the WSS, OSI and velocity were 13.08 ± 2.89 Pa, 0.04 ± 0.01 and 0.07 ± 0.02 m/s, respectively (P < 0.01). After embolization, the WSS, OSI and velocity around the aneurysm neck areas in the recurrent group were significantly higher than those in the stable group.Conclusions: High peak systolic WSS, OSI and velocity around aneurysm neck areas after embolization of paraclinoidal aneurysms may be important factors leading to recurrence.https://www.frontiersin.org/article/10.3389/fneur.2019.00429/fullhemodynamicaneurysmembolizationrecurrencecomputational fluid dynamic |
| spellingShingle | Bin Sheng Degang Wu Jinlong Yuan Shanshui Xu Zhenbao Li Jin Dong Niansheng Lai Xinggen Fang Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization Frontiers in Neurology hemodynamic aneurysm embolization recurrence computational fluid dynamic |
| title | Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization |
| title_full | Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization |
| title_fullStr | Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization |
| title_full_unstemmed | Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization |
| title_short | Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization |
| title_sort | hemodynamic characteristics associated with paraclinoid aneurysm recurrence in patients after embolization |
| topic | hemodynamic aneurysm embolization recurrence computational fluid dynamic |
| url | https://www.frontiersin.org/article/10.3389/fneur.2019.00429/full |
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