Molecularly Imprinted Polymer Based Sensors for Medical Applications
Sensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In recent years, efforts in sensor realm have expanded promptly, and it has alrea...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-03-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/19/6/1279 |
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| author | Yeşeren Saylan Semra Akgönüllü Handan Yavuz Serhat Ünal Adil Denizli |
| author_facet | Yeşeren Saylan Semra Akgönüllü Handan Yavuz Serhat Ünal Adil Denizli |
| author_sort | Yeşeren Saylan |
| collection | DOAJ |
| description | Sensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In recent years, efforts in sensor realm have expanded promptly, and it has already presented a broad range of applications in the fields of medical, pharmaceutical and environmental applications, food safety, and homeland security. In particular, molecularly imprinted polymer based sensors have created a fascinating horizon for surface modification techniques by forming specific recognition cavities for template molecules in the polymeric matrix. This method ensures a broad range of versatility to imprint a variety of biomolecules with different size, three dimensional structure, physical and chemical features. In contrast to complex and time-consuming laboratory surface modification methods, molecular imprinting offers a rapid, sensitive, inexpensive, easy-to-use, and highly selective approaches for sensing, and especially for the applications of diagnosis, screening, and theranostics. Due to its physical and chemical robustness, high stability, low-cost, and reusability features, molecularly imprinted polymer based sensors have become very attractive modalities for such applications with a sensitivity of minute structural changes in the structure of biomolecules. This review aims at discussing the principle of molecular imprinting method, the integration of molecularly imprinted polymers with sensing tools, the recent advances and strategies in molecular imprinting methodologies, their applications in medical, and future outlook on this concept. |
| first_indexed | 2024-04-11T21:56:13Z |
| format | Article |
| id | doaj.art-c00dc66b3d244a73abbbc1ea665b4309 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T21:56:13Z |
| publishDate | 2019-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-c00dc66b3d244a73abbbc1ea665b43092022-12-22T04:01:06ZengMDPI AGSensors1424-82202019-03-01196127910.3390/s19061279s19061279Molecularly Imprinted Polymer Based Sensors for Medical ApplicationsYeşeren Saylan0Semra Akgönüllü1Handan Yavuz2Serhat Ünal3Adil Denizli4Department of Chemistry, Hacettepe University, Ankara 06800, TurkeyDepartment of Chemistry, Hacettepe University, Ankara 06800, TurkeyDepartment of Chemistry, Hacettepe University, Ankara 06800, TurkeyDepartment of Infectious Disease and Clinical Microbiology, Hacettepe University, Ankara 06230, TurkeyDepartment of Chemistry, Hacettepe University, Ankara 06800, TurkeySensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In recent years, efforts in sensor realm have expanded promptly, and it has already presented a broad range of applications in the fields of medical, pharmaceutical and environmental applications, food safety, and homeland security. In particular, molecularly imprinted polymer based sensors have created a fascinating horizon for surface modification techniques by forming specific recognition cavities for template molecules in the polymeric matrix. This method ensures a broad range of versatility to imprint a variety of biomolecules with different size, three dimensional structure, physical and chemical features. In contrast to complex and time-consuming laboratory surface modification methods, molecular imprinting offers a rapid, sensitive, inexpensive, easy-to-use, and highly selective approaches for sensing, and especially for the applications of diagnosis, screening, and theranostics. Due to its physical and chemical robustness, high stability, low-cost, and reusability features, molecularly imprinted polymer based sensors have become very attractive modalities for such applications with a sensitivity of minute structural changes in the structure of biomolecules. This review aims at discussing the principle of molecular imprinting method, the integration of molecularly imprinted polymers with sensing tools, the recent advances and strategies in molecular imprinting methodologies, their applications in medical, and future outlook on this concept.http://www.mdpi.com/1424-8220/19/6/1279medical applicationsmedical sensorsmolecular imprinting |
| spellingShingle | Yeşeren Saylan Semra Akgönüllü Handan Yavuz Serhat Ünal Adil Denizli Molecularly Imprinted Polymer Based Sensors for Medical Applications Sensors medical applications medical sensors molecular imprinting |
| title | Molecularly Imprinted Polymer Based Sensors for Medical Applications |
| title_full | Molecularly Imprinted Polymer Based Sensors for Medical Applications |
| title_fullStr | Molecularly Imprinted Polymer Based Sensors for Medical Applications |
| title_full_unstemmed | Molecularly Imprinted Polymer Based Sensors for Medical Applications |
| title_short | Molecularly Imprinted Polymer Based Sensors for Medical Applications |
| title_sort | molecularly imprinted polymer based sensors for medical applications |
| topic | medical applications medical sensors molecular imprinting |
| url | http://www.mdpi.com/1424-8220/19/6/1279 |
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