Curcumin (Extracted from Tumeric) and its Therapeutic Effects
Background and Objectives: The application of herbal medicine has been rising in recent years. Therefore, it is logical to revise and revive these traditional drugs while identifying their mechanisms of action can result in developing new treatments for many diseases. Curcumin is the most important...
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| Format: | Article |
| Language: | English |
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Golestan University of Medical Sciences
2017-01-01
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| Series: | Jorjani Biomedicine Journal |
| Subjects: | |
| Online Access: | http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-24-87&slc_lang=en&sid=1 |
| _version_ | 1818835704207114240 |
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| author | Arezou khosrojerdi Kazem Mashayekhi Hadi Zare Marzouni |
| author_facet | Arezou khosrojerdi Kazem Mashayekhi Hadi Zare Marzouni |
| author_sort | Arezou khosrojerdi |
| collection | DOAJ |
| description | Background and Objectives: The application of herbal medicine has been rising in recent years. Therefore, it is logical to revise and revive these traditional drugs while identifying their mechanisms of action can result in developing new treatments for many diseases. Curcumin is the most important component of Turmeric with numerous therapeutic properties. We aimed to review the anti-inflammatory and anti-microbial properties of Curcumin and introduce it as a therapeutic molecule in the present article.
Methods: In this review, 121 articles were selected from authenticated electronic resources and scientific library databases such as Pubmed, Medline, Sciencedirect, WOS, DOAJ, SID, Iranmedex, Magiran and Google Scholar search engine in which Curcumin (Turmeric) had been evaluated as a therapeutic molecule from differeny aspects.
Results: Our findings from the literature revealed that immune responses against infectious and inflammatory factors could be fascilitated by Curcumin. However, the low solubility in water and minimal bioavailability which may lead to poor absorbance from gastrointestinal tract, quick metabolization and elimination from blood circulation are the most important problems during oral consumption.
Conclusion: According to the results of the present review article, Curcumin possesses efficient anti-inflammatory, anti-microbial, anti-viral and anti-parasitic properties. However, the low bioavailability of this substance has limited its treatment properties. Nowadays, several mechanisms have been proposed to increase the bioavailability which can improve its absorption. |
| first_indexed | 2024-12-19T02:54:56Z |
| format | Article |
| id | doaj.art-c0221fdbb64640ba8af6b1397e76b437 |
| institution | Directory Open Access Journal |
| issn | 2645-3509 |
| language | English |
| last_indexed | 2024-12-19T02:54:56Z |
| publishDate | 2017-01-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | Jorjani Biomedicine Journal |
| spelling | doaj.art-c0221fdbb64640ba8af6b1397e76b4372022-12-21T20:38:22ZengGolestan University of Medical SciencesJorjani Biomedicine Journal2645-35092017-01-0142120Curcumin (Extracted from Tumeric) and its Therapeutic EffectsArezou khosrojerdi0Kazem Mashayekhi1Hadi Zare Marzouni2 Department of Immunology, Faculty of Medicine, Shahid Beheshti University of Medical Siences, Tehran, Iran Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Background and Objectives: The application of herbal medicine has been rising in recent years. Therefore, it is logical to revise and revive these traditional drugs while identifying their mechanisms of action can result in developing new treatments for many diseases. Curcumin is the most important component of Turmeric with numerous therapeutic properties. We aimed to review the anti-inflammatory and anti-microbial properties of Curcumin and introduce it as a therapeutic molecule in the present article. Methods: In this review, 121 articles were selected from authenticated electronic resources and scientific library databases such as Pubmed, Medline, Sciencedirect, WOS, DOAJ, SID, Iranmedex, Magiran and Google Scholar search engine in which Curcumin (Turmeric) had been evaluated as a therapeutic molecule from differeny aspects. Results: Our findings from the literature revealed that immune responses against infectious and inflammatory factors could be fascilitated by Curcumin. However, the low solubility in water and minimal bioavailability which may lead to poor absorbance from gastrointestinal tract, quick metabolization and elimination from blood circulation are the most important problems during oral consumption. Conclusion: According to the results of the present review article, Curcumin possesses efficient anti-inflammatory, anti-microbial, anti-viral and anti-parasitic properties. However, the low bioavailability of this substance has limited its treatment properties. Nowadays, several mechanisms have been proposed to increase the bioavailability which can improve its absorption.http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-24-87&slc_lang=en&sid=1CurcuminTurmericInflammationInfectionImuune system |
| spellingShingle | Arezou khosrojerdi Kazem Mashayekhi Hadi Zare Marzouni Curcumin (Extracted from Tumeric) and its Therapeutic Effects Jorjani Biomedicine Journal Curcumin Turmeric Inflammation Infection Imuune system |
| title | Curcumin (Extracted from Tumeric) and its Therapeutic Effects |
| title_full | Curcumin (Extracted from Tumeric) and its Therapeutic Effects |
| title_fullStr | Curcumin (Extracted from Tumeric) and its Therapeutic Effects |
| title_full_unstemmed | Curcumin (Extracted from Tumeric) and its Therapeutic Effects |
| title_short | Curcumin (Extracted from Tumeric) and its Therapeutic Effects |
| title_sort | curcumin extracted from tumeric and its therapeutic effects |
| topic | Curcumin Turmeric Inflammation Infection Imuune system |
| url | http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-24-87&slc_lang=en&sid=1 |
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