Even High-Quality CPGs Seldom Include Implementation Strategies

Background: Implementation is a key step in ensuring that high-quality clinical practice guideline (CPG) recommendations are followed and have a positive impact. This step must be planned during CPG development. This study aims to inform professionals tasked with developing and implementing CPGs reg...

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Main Authors: Luciana Pereira de Vasconcelos, Daniela Oliveira De Melo, Airton Tetelbom Stein, Heráclito Barbosa de Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.593894/full
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author Luciana Pereira de Vasconcelos
Daniela Oliveira De Melo
Airton Tetelbom Stein
Heráclito Barbosa de Carvalho
author_facet Luciana Pereira de Vasconcelos
Daniela Oliveira De Melo
Airton Tetelbom Stein
Heráclito Barbosa de Carvalho
author_sort Luciana Pereira de Vasconcelos
collection DOAJ
description Background: Implementation is a key step in ensuring that high-quality clinical practice guideline (CPG) recommendations are followed and have a positive impact. This step must be planned during CPG development. This study aims to inform professionals tasked with developing and implementing CPGs regarding implementation strategies and tools reported in high-quality CPGs for chronic non-communicable diseases (NCDs).Methods: NCD guidelines were selected based on Appraisal of Guideline Research and Evaluation (AGREE) II assessment. CPGs with a score of ≥60% in AGREE II domains 3 (rigor of development), 5 (applicability), and 6 (editorial independence), were considered high quality. The content related to implementation was extracted from CPG full texts and complementary materials. Implementation strategies and tools were assessed and classified using Mazza taxonomy.Results: Twenty high-quality CPGs were selected, most of which were developed by government institutions (16; 80%) with public funding (16; 80%); almost half (9; 45%) addressed the treatment of cardiovascular diseases. The countries with the most high-quality CPGs were the UK (6; 30%) and Colombia (5; 25%). These countries also had the highest average number of strategies, Colombia with 28 (SD = 1) distributed in all levels, and the UK with 15 (SD = 7), concentrating on professional and organizational levels. Although the content of the Colombian CPGs was similar regardless the disease, the CPGs from the UK were specific and contained data-based feedback reports and information on CPG compliance. Implementation strategies most frequently identified were at the professional level, such as distributing reference material (18; 80%) and educating groups of healthcare professionals (18; 80%). At the organizational level, the most frequent strategies involve changes in structure (15; 75%) and service delivery method (13; 65%).Conclusion: Countries with established CPG programs, such as the UK and Colombia, where identified as having the highest number of high-quality CPGs, although CPG implementation content had significant differences. Among high-quality CPGs, the most common implementation strategies were at the professional and organizational levels. There is still room for improvement regarding the implementation strategies report, even among high-quality CPGs, especially concerning monitoring of implementation outcomes and selection of strategies based on relevant implementation barriers.
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spelling doaj.art-c025877917714bbbadb76996cdea02542022-12-21T22:01:39ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122021-01-011110.3389/fphar.2020.593894593894Even High-Quality CPGs Seldom Include Implementation StrategiesLuciana Pereira de Vasconcelos0Daniela Oliveira De Melo1Airton Tetelbom Stein2Heráclito Barbosa de Carvalho3Department of Preventive, Medicine Medical School, São Paulo University, São Paulo, BrazilDepartment of Pharmaceutical Science, Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, São Paulo, BrazilDepartment of Collective Health, Federal University of Health Sciences of Porto Alegre, São Paulo, BrazilDepartment of Preventive, Medicine Medical School, São Paulo University, São Paulo, BrazilBackground: Implementation is a key step in ensuring that high-quality clinical practice guideline (CPG) recommendations are followed and have a positive impact. This step must be planned during CPG development. This study aims to inform professionals tasked with developing and implementing CPGs regarding implementation strategies and tools reported in high-quality CPGs for chronic non-communicable diseases (NCDs).Methods: NCD guidelines were selected based on Appraisal of Guideline Research and Evaluation (AGREE) II assessment. CPGs with a score of ≥60% in AGREE II domains 3 (rigor of development), 5 (applicability), and 6 (editorial independence), were considered high quality. The content related to implementation was extracted from CPG full texts and complementary materials. Implementation strategies and tools were assessed and classified using Mazza taxonomy.Results: Twenty high-quality CPGs were selected, most of which were developed by government institutions (16; 80%) with public funding (16; 80%); almost half (9; 45%) addressed the treatment of cardiovascular diseases. The countries with the most high-quality CPGs were the UK (6; 30%) and Colombia (5; 25%). These countries also had the highest average number of strategies, Colombia with 28 (SD = 1) distributed in all levels, and the UK with 15 (SD = 7), concentrating on professional and organizational levels. Although the content of the Colombian CPGs was similar regardless the disease, the CPGs from the UK were specific and contained data-based feedback reports and information on CPG compliance. Implementation strategies most frequently identified were at the professional level, such as distributing reference material (18; 80%) and educating groups of healthcare professionals (18; 80%). At the organizational level, the most frequent strategies involve changes in structure (15; 75%) and service delivery method (13; 65%).Conclusion: Countries with established CPG programs, such as the UK and Colombia, where identified as having the highest number of high-quality CPGs, although CPG implementation content had significant differences. Among high-quality CPGs, the most common implementation strategies were at the professional and organizational levels. There is still room for improvement regarding the implementation strategies report, even among high-quality CPGs, especially concerning monitoring of implementation outcomes and selection of strategies based on relevant implementation barriers.https://www.frontiersin.org/articles/10.3389/fphar.2020.593894/fullclinical practice guidelineagree Ⅱappraisal (evaluation)applicabilitynon communicable chronic diseasesimplementation tools
spellingShingle Luciana Pereira de Vasconcelos
Daniela Oliveira De Melo
Airton Tetelbom Stein
Heráclito Barbosa de Carvalho
Even High-Quality CPGs Seldom Include Implementation Strategies
Frontiers in Pharmacology
clinical practice guideline
agree Ⅱ
appraisal (evaluation)
applicability
non communicable chronic diseases
implementation tools
title Even High-Quality CPGs Seldom Include Implementation Strategies
title_full Even High-Quality CPGs Seldom Include Implementation Strategies
title_fullStr Even High-Quality CPGs Seldom Include Implementation Strategies
title_full_unstemmed Even High-Quality CPGs Seldom Include Implementation Strategies
title_short Even High-Quality CPGs Seldom Include Implementation Strategies
title_sort even high quality cpgs seldom include implementation strategies
topic clinical practice guideline
agree Ⅱ
appraisal (evaluation)
applicability
non communicable chronic diseases
implementation tools
url https://www.frontiersin.org/articles/10.3389/fphar.2020.593894/full
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