Mitochondria-Targeted Delivery of Camptothecin Based on HPMA Copolymer for Metastasis Suppression

Mitochondria-Targeted Delivery of Camptothecin Based on HPMA Copolymer for Metastasis Suppression

Poor anti-metastasis effects and side-effects remain a challenge for the clinical application of camptothecin (CPT). Mitochondria can be a promising target for the treatment of metastatic tumors due to their vital roles in providing energy supply, upregulating pro-metastatic factors, and controlling...

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Bibliographic Details
Main Authors: Xiaoli Yi, Yue Yan, Xinran Shen, Lian Li, Yuan Huang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
camptothecin
metastasis
mitochondria
2-(dimethylamino) ethyl methacrylate
Online Access:https://www.mdpi.com/1999-4923/14/8/1534

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