Falsely undetectable TSH in a euthyroid patient

Abstract Background Measuring thyroid hormone levels is essential and helpful in the diagnosis of thyroid diseases. Case presentation We had a patient with undetectable serum TSH level by the Siemens immunoassay, whereas by ELISA and Roche-Abott immunoassay, serum level of TSH was in the normal rang...

Full description

Bibliographic Details
Main Authors: Monireh Rahimkhani, Kiana Kazemian, Rashid Ramezani Daryasari
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Thyroid Research
Online Access:https://doi.org/10.1186/s13044-020-0076-y
_version_ 1818854913538523136
author Monireh Rahimkhani
Kiana Kazemian
Rashid Ramezani Daryasari
author_facet Monireh Rahimkhani
Kiana Kazemian
Rashid Ramezani Daryasari
author_sort Monireh Rahimkhani
collection DOAJ
description Abstract Background Measuring thyroid hormone levels is essential and helpful in the diagnosis of thyroid diseases. Case presentation We had a patient with undetectable serum TSH level by the Siemens immunoassay, whereas by ELISA and Roche-Abott immunoassay, serum level of TSH was in the normal range. Conclusion If the result of TSH level revealed very low or undetectable through one specific method, it should not be considered necessarily as a symptom of hyperthyroidism. It is to be requested to measure by the other methods with other devices too.
first_indexed 2024-12-19T08:00:16Z
format Article
id doaj.art-c027f33717544def9a82c0a0fe1cfe0f
institution Directory Open Access Journal
issn 1756-6614
language English
last_indexed 2024-12-19T08:00:16Z
publishDate 2020-01-01
publisher BMC
record_format Article
series Thyroid Research
spelling doaj.art-c027f33717544def9a82c0a0fe1cfe0f2022-12-21T20:29:54ZengBMCThyroid Research1756-66142020-01-011311310.1186/s13044-020-0076-yFalsely undetectable TSH in a euthyroid patientMonireh Rahimkhani0Kiana Kazemian1Rashid Ramezani Daryasari2Department of Lab Medical Sciences, Faculty of allied medical Sciences, Tehran University of Medical SciencesAl-mahdi Clinic, Tehran University of Medical SciencesAl-mahdi Clinic, Tehran University of Medical SciencesAbstract Background Measuring thyroid hormone levels is essential and helpful in the diagnosis of thyroid diseases. Case presentation We had a patient with undetectable serum TSH level by the Siemens immunoassay, whereas by ELISA and Roche-Abott immunoassay, serum level of TSH was in the normal range. Conclusion If the result of TSH level revealed very low or undetectable through one specific method, it should not be considered necessarily as a symptom of hyperthyroidism. It is to be requested to measure by the other methods with other devices too.https://doi.org/10.1186/s13044-020-0076-y
spellingShingle Monireh Rahimkhani
Kiana Kazemian
Rashid Ramezani Daryasari
Falsely undetectable TSH in a euthyroid patient
Thyroid Research
title Falsely undetectable TSH in a euthyroid patient
title_full Falsely undetectable TSH in a euthyroid patient
title_fullStr Falsely undetectable TSH in a euthyroid patient
title_full_unstemmed Falsely undetectable TSH in a euthyroid patient
title_short Falsely undetectable TSH in a euthyroid patient
title_sort falsely undetectable tsh in a euthyroid patient
url https://doi.org/10.1186/s13044-020-0076-y
work_keys_str_mv AT monirehrahimkhani falselyundetectabletshinaeuthyroidpatient
AT kianakazemian falselyundetectabletshinaeuthyroidpatient
AT rashidramezanidaryasari falselyundetectabletshinaeuthyroidpatient