Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic Epilepsy

We analyzed 42 pregnancy, delivery, and postpartum period records in women with juvenile myoclonic epilepsy (JME). In most cases, the course of JME was favorable during pregnancy; so administration of subtherapeutic dosages of AEDs in the first and second trimesters of pregnancy can be recommended....

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Main Author: A. V. Yakunina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2014-07-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/407
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author A. V. Yakunina
author_facet A. V. Yakunina
author_sort A. V. Yakunina
collection DOAJ
description We analyzed 42 pregnancy, delivery, and postpartum period records in women with juvenile myoclonic epilepsy (JME). In most cases, the course of JME was favorable during pregnancy; so administration of subtherapeutic dosages of AEDs in the first and second trimesters of pregnancy can be recommended. Epilepsy decompensation occurred in the postpartum period in 40.5% of cases. Because of a significant risk of epilepsy aggravation during the postpartum period, it is reasonable to increase the dosage of AEDs up to the therapeutic one by the time of expected delivery. We recommend administering AEDs at this dosage for at least three months after the delivery. Neither birth weight or height deviations, nor abnormal Apgar score, nor congenital disorders were revealed in newborns.
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spelling doaj.art-c02889d4104b4753b5b31cee8c34a4c82023-03-13T08:42:14ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422014-07-0161S131710.14412/2074-2711-2014-1S-13-17397Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic EpilepsyA. V. Yakunina0Samara State Medical University, SamaraWe analyzed 42 pregnancy, delivery, and postpartum period records in women with juvenile myoclonic epilepsy (JME). In most cases, the course of JME was favorable during pregnancy; so administration of subtherapeutic dosages of AEDs in the first and second trimesters of pregnancy can be recommended. Epilepsy decompensation occurred in the postpartum period in 40.5% of cases. Because of a significant risk of epilepsy aggravation during the postpartum period, it is reasonable to increase the dosage of AEDs up to the therapeutic one by the time of expected delivery. We recommend administering AEDs at this dosage for at least three months after the delivery. Neither birth weight or height deviations, nor abnormal Apgar score, nor congenital disorders were revealed in newborns.https://nnp.ima-press.net/nnp/article/view/407pregnancyjuvenile myoclonic epilepsy.
spellingShingle A. V. Yakunina
Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic Epilepsy
Неврология, нейропсихиатрия, психосоматика
pregnancy
juvenile myoclonic epilepsy.
title Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic Epilepsy
title_full Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic Epilepsy
title_fullStr Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic Epilepsy
title_full_unstemmed Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic Epilepsy
title_short Features of the Gestation Course, Delivery, and Postpartum Period in Women with Juvenile Myoclonic Epilepsy
title_sort features of the gestation course delivery and postpartum period in women with juvenile myoclonic epilepsy
topic pregnancy
juvenile myoclonic epilepsy.
url https://nnp.ima-press.net/nnp/article/view/407
work_keys_str_mv AT avyakunina featuresofthegestationcoursedeliveryandpostpartumperiodinwomenwithjuvenilemyoclonicepilepsy