A platform for actively loading cargo RNA to elucidate limiting steps in EV-mediated delivery

A platform for actively loading cargo RNA to elucidate limiting steps in EV-mediated delivery

Extracellular vesicles (EVs) mediate intercellular communication through transfer of RNA and protein between cells. Thus, understanding how cargo molecules are loaded and delivered by EVs is of central importance for elucidating the biological roles of EVs and developing EV-based therapeutics. While...

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Bibliographic Details
Main Authors: Michelle E. Hung, Joshua N. Leonard
Format: Article
Language:English
Published: Wiley 2016-05-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
exosomes
microvesicles
active loading
Lamp2b
VSVG
MS2 coat protein dimer
CD63
Online Access:http://www.journalofextracellularvesicles.net/index.php/jev/article/view/31027/pdf_63

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