Identification of a TGF-β signaling-related gene signature for prediction of immunotherapy and targeted therapy for lung adenocarcinoma

Identification of a TGF-β signaling-related gene signature for prediction of immunotherapy and targeted therapy for lung adenocarcinoma

Abstract Background Transforming growth factor (TGF)-β signaling functions importantly in regulating tumor microenvironment (TME). This study developed a prognostic gene signature based on TGF-β signaling-related genes for predicting clinical outcome of patients with lung adenocarcinoma (LUAD). Meth...

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Bibliographic Details
Main Authors: Qian Yu, Liang Zhao, Xue-xin Yan, Ye Li, Xin-yu Chen, Xiao-hua Hu, Qing Bu, Xiao-ping Lv
Format: Article
Language:English
Published: BMC 2022-06-01
Series:World Journal of Surgical Oncology
Subjects:
TGF-β signaling
Lung adenocarcinoma
Risk model
Prognosis
Tumor microenvironment
Immunotherapy
Online Access:https://doi.org/10.1186/s12957-022-02595-1

Internet

https://doi.org/10.1186/s12957-022-02595-1

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