Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia

<p>The paper presents an assessment of treatment efficacy in chronic lymphocytic leukemia CLL patients according to chemotherapy type and initial renal function. The high efficacy of chemotherapy with fludarabine in CLL patients with or without renal failure at diagnosis was revealed. However,...

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Main Authors: A. K. Nikitina, N. O. Saraeva
Format: Article
Language:Russian
Published: ABV-press 2015-06-01
Series:Онкогематология
Subjects:
Online Access:http://oncohematology.abvpress.ru/index.php/ongm/article/view/135
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author A. K. Nikitina
N. O. Saraeva
author_facet A. K. Nikitina
N. O. Saraeva
author_sort A. K. Nikitina
collection DOAJ
description <p>The paper presents an assessment of treatment efficacy in chronic lymphocytic leukemia CLL patients according to chemotherapy type and initial renal function. The high efficacy of chemotherapy with fludarabine in CLL patients with or without renal failure at diagnosis was revealed. However, regardless of chemotherapy type initial treatment response was worse in patients with renal failure.</p>
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spelling doaj.art-c03b781862be4bd09e99a7252d990b892023-08-02T09:10:45ZrusABV-pressОнкогематология1818-83462015-06-011012428150Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemiaA. K. Nikitina0N. O. Saraeva1Irkutsk State Medical University; 1 Krasnogo Vosstaniya St., Irkutsk, 664003, RussiaIrkutsk State Medical University; 1 Krasnogo Vosstaniya St., Irkutsk, 664003, Russia<p>The paper presents an assessment of treatment efficacy in chronic lymphocytic leukemia CLL patients according to chemotherapy type and initial renal function. The high efficacy of chemotherapy with fludarabine in CLL patients with or without renal failure at diagnosis was revealed. However, regardless of chemotherapy type initial treatment response was worse in patients with renal failure.</p>http://oncohematology.abvpress.ru/index.php/ongm/article/view/135renal failurechronic lymphocytic leukemiachemotherapyfludarabine
spellingShingle A. K. Nikitina
N. O. Saraeva
Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia
Онкогематология
renal failure
chronic lymphocytic leukemia
chemotherapy
fludarabine
title Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia
title_full Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia
title_fullStr Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia
title_full_unstemmed Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia
title_short Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia
title_sort initial renal function and type of chemotherapy impact on treatment efficacy in patients with chronic lymphocytic leukemia
topic renal failure
chronic lymphocytic leukemia
chemotherapy
fludarabine
url http://oncohematology.abvpress.ru/index.php/ongm/article/view/135
work_keys_str_mv AT aknikitina initialrenalfunctionandtypeofchemotherapyimpactontreatmentefficacyinpatientswithchroniclymphocyticleukemia
AT nosaraeva initialrenalfunctionandtypeofchemotherapyimpactontreatmentefficacyinpatientswithchroniclymphocyticleukemia