Sphingosine 1-Phosphate Receptors and Metabolic Enzymes as Druggable Targets for Brain Diseases
The central nervous system is characterized by a high content of sphingolipids and by a high diversity in terms of different structures. Stage- and cell-specific sphingolipid metabolism and expression are crucial for brain development and maintenance toward adult age. On the other hand, deep dysregu...
Main Authors: | Sara Grassi, Laura Mauri, Simona Prioni, Livia Cabitta, Sandro Sonnino, Alessandro Prinetti, Paola Giussani |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-07-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2019.00807/full |
Similar Items
-
Corrigendum: Sphingosine 1-Phosphate: A Novel Target for Lung Disorders
by: Sabira Mohammed, et al.
Published: (2018-07-01) -
Sphingosine 1-Phosphate Receptor 4 Expression in Colorectal Cancer Patients
by: Suchittra SAMUHASANEETO, et al.
Published: (2016-06-01) -
The Anti-Infectious Role of Sphingosine in Microbial Diseases
by: Yuqing Wu, et al.
Published: (2021-05-01) -
The Role of Sphingolipids and Sphingosine-1-phosphate—Sphingosine-1-phosphate-receptor Signaling in Psoriasis
by: Kana Masuda-Kuroki, et al.
Published: (2023-09-01) -
A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke
by: Alexandra Lucaciu, et al.
Published: (2020-08-01)