Differences in the Shiga Toxin (Stx) 2a Phage Regulatory Switch Region Influence Stx2 Localization and Virulence of Stx-Producing <i>Escherichia coli</i> in Mice

Differences in the Shiga Toxin (Stx) 2a Phage Regulatory Switch Region Influence Stx2 Localization and Virulence of Stx-Producing <i>Escherichia coli</i> in Mice

Shiga toxin (Stx)-producing <i>Escherichia coli</i> (STEC) is a major cause of foodborne illness globally, and infection with serotype O157:H7 is associated with increased risk of hospitalization and death in the U.S. The Stxs are encoded on a temperate bacteriophage (<i>stx</i&...

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Bibliographic Details
Main Authors: Rama R. Atitkar, Angela R. Melton-Celsa
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Microorganisms
Subjects:
<i>Escherichia coli</i>
Shiga toxin
phage
CI repressor
<i>recA</i>
Online Access:https://www.mdpi.com/2076-2607/11/8/1925

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