Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies

We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases ha...

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Main Authors: Keiko Hatano, Hideyuki Matsumoto, Akihiko Mitsutake, Junko Yoshimura, Aya Nomura, Sumihisa Imakado, Yukitoshi Takahashi, Hideji Hashida
Format: Article
Language:English
Published: Karger Publishers 2018-08-01
Series:Case Reports in Neurology
Subjects:
Online Access:https://www.karger.com/Article/FullText/491690
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author Keiko Hatano
Hideyuki Matsumoto
Akihiko Mitsutake
Junko Yoshimura
Aya Nomura
Sumihisa Imakado
Yukitoshi Takahashi
Hideji Hashida
author_facet Keiko Hatano
Hideyuki Matsumoto
Akihiko Mitsutake
Junko Yoshimura
Aya Nomura
Sumihisa Imakado
Yukitoshi Takahashi
Hideji Hashida
author_sort Keiko Hatano
collection DOAJ
description We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases has not yet been reported. We speculate that the total of 18 drugs needed for the treatment of encephalitis might have increased the risk of TEN. Similar reports would be required to elucidate the pathophysiology of the co-existence.
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spelling doaj.art-c04b2da563d84b9cb14a30afcc6183cd2022-12-22T00:01:45ZengKarger PublishersCase Reports in Neurology1662-680X2018-08-0110220721210.1159/000491690491690Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor AntibodiesKeiko HatanoHideyuki MatsumotoAkihiko MitsutakeJunko YoshimuraAya NomuraSumihisa ImakadoYukitoshi TakahashiHideji HashidaWe report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases has not yet been reported. We speculate that the total of 18 drugs needed for the treatment of encephalitis might have increased the risk of TEN. Similar reports would be required to elucidate the pathophysiology of the co-existence.https://www.karger.com/Article/FullText/491690Anti-glutamate receptor antibodiesAutoimmune limbic encephalitisToxic epidermal necrolysis (TEN)
spellingShingle Keiko Hatano
Hideyuki Matsumoto
Akihiko Mitsutake
Junko Yoshimura
Aya Nomura
Sumihisa Imakado
Yukitoshi Takahashi
Hideji Hashida
Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
Case Reports in Neurology
Anti-glutamate receptor antibodies
Autoimmune limbic encephalitis
Toxic epidermal necrolysis (TEN)
title Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_full Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_fullStr Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_full_unstemmed Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_short Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies
title_sort toxic epidermal necrolysis in a patient with autoimmune limbic encephalitis with anti glutamate receptor antibodies
topic Anti-glutamate receptor antibodies
Autoimmune limbic encephalitis
Toxic epidermal necrolysis (TEN)
url https://www.karger.com/Article/FullText/491690
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