The Inhibitory Effect of Extra Virgin Olive Oil and Its Active Compound Oleocanthal on Prostaglandin-Induced Uterine Hypercontraction and Pain—Ex Vivo and In Vivo Study

The Inhibitory Effect of Extra Virgin Olive Oil and Its Active Compound Oleocanthal on Prostaglandin-Induced Uterine Hypercontraction and Pain—Ex Vivo and In Vivo Study

Primary dysmenorrhea is a common occurrence in adolescent women and is a type of chronic inflammation. Dysmenorrhea is due to an increase in oxidative stress, which increases cyclooxygenase-2 (COX-2) expression, increases the concentration of prostaglandin F2α (PGF2α), and increases the calcium conc...

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Bibliographic Details
Main Authors: Yi-Fen Chiang, Hui-Chih Hung, Hsin-Yuan Chen, Ko-Chieh Huang, Po-Han Lin, Jen-Yun Chang, Tsui-Chin Huang, Shih-Min Hsia
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Nutrients
Subjects:
primary dysmenorrhea
extra virgin olive oil
oleocanthal
mice writhing model
Online Access:https://www.mdpi.com/2072-6643/12/10/3012

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