Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces
ABSTRACTAntibody-mediated delivery of immunogenic viral CD8+ T-cell epitopes to redirect virus-specific T cells toward cancer cells is a promising new therapeutic avenue to increase the immunogenicity of tumors. Multiple strategies for viral epitope delivery have been shown to be effective. So far,...
Main Authors: | W. van der Wulp, W. Luu, M. E. Ressing, J. Schuurman, S. I. van Kasteren, L. Guelen, R. C. Hoeben, B. Bleijlevens, M. H. M. Heemskerk |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
|
Series: | mAbs |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2024.2329321 |
Similar Items
-
Comparison of methods generating antibody-epitope conjugates for targeting cancer with virus-specific T cells
by: Willemijn van der Wulp, et al.
Published: (2023-05-01) -
T and B cell epitope analysis for the immunogenicity evaluation and mitigation of antibody-based therapeutics
by: Ruoxuan Sun, et al.
Published: (2024-12-01) -
Bispecific antibodies for the treatment of relapsed/refractory multiple myeloma: updates and future perspectives
by: Ricardo D. Parrondo, et al.
Published: (2024-04-01) -
T Cell Bispecific Antibodies: An Antibody-Based Delivery System for Inducing Antitumor Immunity
by: Daisuke Kamakura, et al.
Published: (2021-11-01) -
T‐cell redirecting bispecific antibodies in multiple myeloma: Current landscape and future directions
by: Chloe O'Neill, et al.
Published: (2023-08-01)