Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving Technique

Background:. Retromuscular hernia repairs (RHRs) decrease hernia recurrence and surgical site infections but can cause significant pain. We aimed to determine if pain and postoperative outcomes differed when comparing suture fixation (SF) of mesh to fibrin glue fixation (FGF). Methods:. Patients und...

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Main Authors: Irfan A. Rhemtulla, MD, MS, Michael G. Tecce, DO, Robyn B. Broach, PhD, Charles A. Messa, IV, BS, Jaclyn T. Mauch, BA, John P. Fischer, MD, MPH
Format: Article
Language:English
Published: Wolters Kluwer 2019-04-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002184
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author Irfan A. Rhemtulla, MD, MS
Michael G. Tecce, DO
Robyn B. Broach, PhD
Charles A. Messa, IV, BS
Jaclyn T. Mauch, BA
John P. Fischer, MD, MPH
author_facet Irfan A. Rhemtulla, MD, MS
Michael G. Tecce, DO
Robyn B. Broach, PhD
Charles A. Messa, IV, BS
Jaclyn T. Mauch, BA
John P. Fischer, MD, MPH
author_sort Irfan A. Rhemtulla, MD, MS
collection DOAJ
description Background:. Retromuscular hernia repairs (RHRs) decrease hernia recurrence and surgical site infections but can cause significant pain. We aimed to determine if pain and postoperative outcomes differed when comparing suture fixation (SF) of mesh to fibrin glue fixation (FGF). Methods:. Patients undergoing RHR (n = 87) between December 1, 2015 and December 31, 2017 were retrospectively identified. Patients received SF of mesh (n = 59, 67.8%) before the senior author changing his technique to FGF (n = 28, 32.2%). These 2 cohorts were matched (age, body mass index, number of prior repairs, mesh type, defect size, and wound class). Outcomes were analyzed using a matched pairs design with multivariable linear regression. Results:. Two matched groups (21 FGF and 21 SF) were analyzed (45.2% female, average age 56 years, average body mass index 34.7 kg/m2, and average defect size 330 cm2). Statistical significance was observed for FGF compared with SF: length of stay (3.7 versus 7.1 days, P = 0.032), time with a drain (17.2 versus 27.5 days, P = 0.012), 30-day postoperative visits (2 versus 3, P = 0.003), pain scores (5.2 versus 3.1, P = 0.019) and activity within the first 24 hours (walking versus sitting, P = 0.002). Operative time decreased by 23.1 minutes (P = 0.352) and postoperative narcotic represcription (3 versus. 8 patients, p=0.147) also decreased. Average cost for patients receiving SF was $36,152 compared to $21,782 for FGF (P = 0.035). Conclusions:. Sutureless RHR using FGF may result in decreased pain when compared with a matched cohort receiving SF, translating to enhanced recovery time, shortened hospital stay, and decreased costs.
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spelling doaj.art-c04d25573e634b3985e0d59228a13f5d2022-12-21T23:49:55ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742019-04-0174e218410.1097/GOX.0000000000002184201904000-00014Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving TechniqueIrfan A. Rhemtulla, MD, MS0Michael G. Tecce, DO1Robyn B. Broach, PhD2Charles A. Messa, IV, BS3Jaclyn T. Mauch, BA4John P. Fischer, MD, MPH5From the Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.From the Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.From the Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.From the Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.From the Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.From the Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.Background:. Retromuscular hernia repairs (RHRs) decrease hernia recurrence and surgical site infections but can cause significant pain. We aimed to determine if pain and postoperative outcomes differed when comparing suture fixation (SF) of mesh to fibrin glue fixation (FGF). Methods:. Patients undergoing RHR (n = 87) between December 1, 2015 and December 31, 2017 were retrospectively identified. Patients received SF of mesh (n = 59, 67.8%) before the senior author changing his technique to FGF (n = 28, 32.2%). These 2 cohorts were matched (age, body mass index, number of prior repairs, mesh type, defect size, and wound class). Outcomes were analyzed using a matched pairs design with multivariable linear regression. Results:. Two matched groups (21 FGF and 21 SF) were analyzed (45.2% female, average age 56 years, average body mass index 34.7 kg/m2, and average defect size 330 cm2). Statistical significance was observed for FGF compared with SF: length of stay (3.7 versus 7.1 days, P = 0.032), time with a drain (17.2 versus 27.5 days, P = 0.012), 30-day postoperative visits (2 versus 3, P = 0.003), pain scores (5.2 versus 3.1, P = 0.019) and activity within the first 24 hours (walking versus sitting, P = 0.002). Operative time decreased by 23.1 minutes (P = 0.352) and postoperative narcotic represcription (3 versus. 8 patients, p=0.147) also decreased. Average cost for patients receiving SF was $36,152 compared to $21,782 for FGF (P = 0.035). Conclusions:. Sutureless RHR using FGF may result in decreased pain when compared with a matched cohort receiving SF, translating to enhanced recovery time, shortened hospital stay, and decreased costs.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002184
spellingShingle Irfan A. Rhemtulla, MD, MS
Michael G. Tecce, DO
Robyn B. Broach, PhD
Charles A. Messa, IV, BS
Jaclyn T. Mauch, BA
John P. Fischer, MD, MPH
Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving Technique
Plastic and Reconstructive Surgery, Global Open
title Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving Technique
title_full Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving Technique
title_fullStr Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving Technique
title_full_unstemmed Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving Technique
title_short Retromuscular Mesh Repair Using Fibrin Glue: Early Outcomes and Cost-effectiveness of an Evolving Technique
title_sort retromuscular mesh repair using fibrin glue early outcomes and cost effectiveness of an evolving technique
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002184
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