Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting
Based on our prior research, we synthesized iron-oxide nanoparticles (IONPs) in two shapes (spherical and cubic) and sized them for the current inquiry. This research examined the magnetic, rheological, and sedimentation properties of the suspensions containing PEG-coated IONPs, considering that bot...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Magnetochemistry |
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| Online Access: | https://www.mdpi.com/2312-7481/9/4/99 |
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| author | Maria-Cristina Ioncica Sulalit Bandyopadhyay Nesrine Bali Vlad Socoliuc Sandor I. Bernad |
| author_facet | Maria-Cristina Ioncica Sulalit Bandyopadhyay Nesrine Bali Vlad Socoliuc Sandor I. Bernad |
| author_sort | Maria-Cristina Ioncica |
| collection | DOAJ |
| description | Based on our prior research, we synthesized iron-oxide nanoparticles (IONPs) in two shapes (spherical and cubic) and sized them for the current inquiry. This research examined the magnetic, rheological, and sedimentation properties of the suspensions containing PEG-coated IONPs, considering that both produced particles are intended to be employed for magnetic targeting applications. The saturation magnetization of both IONPs was lower than the magnetite domain magnetization of 92 emu/g due to the surfactant and the dead surface magnetic layer. Under each investigated magnetic field (0, 34 and 183 mT), the shear viscosity behaviour of the MNP suspensions of both kinds was comparable. Shear thinning behaviour was seen for both particle suspensions in the low shear rate area (0.1 s<sup>−1</sup> to 1 s<sup>−1</sup>). The rheological curves from this paper show that the suspensions present a higher viscosity at lower shear rates for spherical and cubic PEG-coated nanoparticles when a magnetic field is applied. The aggregation behaviour demonstrates that cubic-shaped IONPs are more stable throughout time, with hydrodynamic diameter measurements showing a relatively slow variation of the DLS size distribution from 250 nm to 210 nm in the first 600 s; contrarily, the hydrodynamic diameter of spherical IONPs fluctuated significantly, from 855 nm to 460 nm. Another key finding relates to the sedimentation profile, specifically that PEG-coated IONPs with spherical shapes have a stronger tendency to sediment than those with cubic forms, which are more stable. |
| first_indexed | 2024-03-11T04:49:24Z |
| format | Article |
| id | doaj.art-c04efa95b75746c3be070c481b934177 |
| institution | Directory Open Access Journal |
| issn | 2312-7481 |
| language | English |
| last_indexed | 2024-03-11T04:49:24Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Magnetochemistry |
| spelling | doaj.art-c04efa95b75746c3be070c481b9341772023-11-17T20:09:41ZengMDPI AGMagnetochemistry2312-74812023-04-01949910.3390/magnetochemistry9040099Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic TargetingMaria-Cristina Ioncica0Sulalit Bandyopadhyay1Nesrine Bali2Vlad Socoliuc3Sandor I. Bernad4Research Center for Engineering of Systems with Complex Fluids, Politehnica University Timisoara, Mihai Viteazul Str. 1, 300222 Timisoara, RomaniaParticle Engineering Centre, Department of Chemical Engineering, Faculty of Natural Science, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, NorwayParticle Engineering Centre, Department of Chemical Engineering, Faculty of Natural Science, Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, NorwayRomanian Academy-Timisoara Branch, Centre for Fundamental and Advanced Technical Research, Mihai Viteazul Str. 24, 300223 Timisoara, RomaniaResearch Center for Engineering of Systems with Complex Fluids, Politehnica University Timisoara, Mihai Viteazul Str. 1, 300222 Timisoara, RomaniaBased on our prior research, we synthesized iron-oxide nanoparticles (IONPs) in two shapes (spherical and cubic) and sized them for the current inquiry. This research examined the magnetic, rheological, and sedimentation properties of the suspensions containing PEG-coated IONPs, considering that both produced particles are intended to be employed for magnetic targeting applications. The saturation magnetization of both IONPs was lower than the magnetite domain magnetization of 92 emu/g due to the surfactant and the dead surface magnetic layer. Under each investigated magnetic field (0, 34 and 183 mT), the shear viscosity behaviour of the MNP suspensions of both kinds was comparable. Shear thinning behaviour was seen for both particle suspensions in the low shear rate area (0.1 s<sup>−1</sup> to 1 s<sup>−1</sup>). The rheological curves from this paper show that the suspensions present a higher viscosity at lower shear rates for spherical and cubic PEG-coated nanoparticles when a magnetic field is applied. The aggregation behaviour demonstrates that cubic-shaped IONPs are more stable throughout time, with hydrodynamic diameter measurements showing a relatively slow variation of the DLS size distribution from 250 nm to 210 nm in the first 600 s; contrarily, the hydrodynamic diameter of spherical IONPs fluctuated significantly, from 855 nm to 460 nm. Another key finding relates to the sedimentation profile, specifically that PEG-coated IONPs with spherical shapes have a stronger tendency to sediment than those with cubic forms, which are more stable.https://www.mdpi.com/2312-7481/9/4/99magnetic nanoparticlesparticle synthesisparticle targetingnanoparticle morphologymagnetic characteristicsbiomedical applications |
| spellingShingle | Maria-Cristina Ioncica Sulalit Bandyopadhyay Nesrine Bali Vlad Socoliuc Sandor I. Bernad Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting Magnetochemistry magnetic nanoparticles particle synthesis particle targeting nanoparticle morphology magnetic characteristics biomedical applications |
| title | Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting |
| title_full | Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting |
| title_fullStr | Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting |
| title_full_unstemmed | Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting |
| title_short | Investigation of Cubic and Spherical IONPs’ Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting |
| title_sort | investigation of cubic and spherical ionps rheological characteristics and aggregation patterns from the perspective of magnetic targeting |
| topic | magnetic nanoparticles particle synthesis particle targeting nanoparticle morphology magnetic characteristics biomedical applications |
| url | https://www.mdpi.com/2312-7481/9/4/99 |
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