Bone marrow mesenchymal stem cell‐derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway

Bone marrow mesenchymal stem cell‐derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway

Obesity is a common chronic metabolic disease that induces chronic systemic inflammation in the body, eventually leading to related complications such as insulin resistance (IR), type 2 diabetes mellitus, and metabolic syndromes such as cardiovascular disease. Exosomes transfer bioactive substances...

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Bibliographic Details
Main Authors: Hongwei Shi, Xiaojing Hao, Yaqin Sun, Huilin Zhang, Yating Zhao, Bin Wang, Jiayin Lu, Wei Hou, Yi Yan, Xiuju Yu, Linli Xue, Xiaomao Luo, Haidong Wang
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:FEBS Open Bio
Subjects:
BMSC
exosomes
inflammation
insulin resistance
obesity
PI3K/AKT
Online Access:https://doi.org/10.1002/2211-5463.13615

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