EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS
Aim. To assess the relation of epicardial fat tissue thickness (EFTT) and other metabolic risk factors with the index of coronary atherosclerosis Spread (CASI) in obese patients. Material and methods. Totally 186 men included (54,4±9,1 y.o.) with coronary heart disease (CHD) and obesity. By the resu...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2015-04-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/264 |
| _version_ | 1827063855488958464 |
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| author | G. A. Chumakova N. G. Veselovskaya A. V. Ott O. V. Gritsenko |
| author_facet | G. A. Chumakova N. G. Veselovskaya A. V. Ott O. V. Gritsenko |
| author_sort | G. A. Chumakova |
| collection | DOAJ |
| description | Aim. To assess the relation of epicardial fat tissue thickness (EFTT) and other metabolic risk factors with the index of coronary atherosclerosis Spread (CASI) in obese patients. Material and methods. Totally 186 men included (54,4±9,1 y.o.) with coronary heart disease (CHD) and obesity. By the results of coronary arteriography we calculated Gensini Score of CASI. All patients underwent laboratory tests with the measurement of basic and additional metabolic risk factors and echocardiography with EFFT measurement. Results. By the data of regression analysis we selected 7 predictors significantly related to EFTT: CASI (β=0,390), resistine (β=0,453), glucose (β=152), adiponectine (β=-0,175), high density lipoproteides cholesterol (β=-0,138), interleukine-6 (β=0,118), and tumor necrosis factor-α (β=0,117). Measurement of the predictors values led in 52,1% to the changes of CASI value (R²=0,521). Conclusion. In obese patients the assessment of the parameters described makes possible to circle a high risk group for unsymptomatic CHD forms with the aim for on-time investigation of patients and for early preventive interventions. |
| first_indexed | 2024-04-10T03:36:39Z |
| format | Article |
| id | doaj.art-c0535d19ece74b9fbcfc6c98eea745db |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2025-03-19T22:37:53Z |
| publishDate | 2015-04-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-c0535d19ece74b9fbcfc6c98eea745db2024-10-17T12:21:34Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252015-04-01142354010.15829/1728-8800-2015-2-35-40263EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSISG. A. Chumakova0N. G. Veselovskaya1A. V. Ott2O. V. Gritsenko3Altay State Medical University, Barnaul, Russia; FSBI SRI of Complex Problems of Cardiovascular Diseases SD RAMS. Kemerovo, RussiaFSBI SRI of Complex Problems of Cardiovascular Diseases SD RAMS. Kemerovo, Russia; Altay Regional Cardiological Dispensary. Barnaul, RussiaAltay Regional Cardiological Dispensary. Barnaul, RussiaFSBI SRI of Complex Problems of Cardiovascular Diseases SD RAMS. Kemerovo, Russia; Altay Regional Cardiological Dispensary. Barnaul, RussiaAim. To assess the relation of epicardial fat tissue thickness (EFTT) and other metabolic risk factors with the index of coronary atherosclerosis Spread (CASI) in obese patients. Material and methods. Totally 186 men included (54,4±9,1 y.o.) with coronary heart disease (CHD) and obesity. By the results of coronary arteriography we calculated Gensini Score of CASI. All patients underwent laboratory tests with the measurement of basic and additional metabolic risk factors and echocardiography with EFFT measurement. Results. By the data of regression analysis we selected 7 predictors significantly related to EFTT: CASI (β=0,390), resistine (β=0,453), glucose (β=152), adiponectine (β=-0,175), high density lipoproteides cholesterol (β=-0,138), interleukine-6 (β=0,118), and tumor necrosis factor-α (β=0,117). Measurement of the predictors values led in 52,1% to the changes of CASI value (R²=0,521). Conclusion. In obese patients the assessment of the parameters described makes possible to circle a high risk group for unsymptomatic CHD forms with the aim for on-time investigation of patients and for early preventive interventions.https://cardiovascular.elpub.ru/jour/article/view/264coronary atherosclerosismetabolic risk factorsepicardial obesity |
| spellingShingle | G. A. Chumakova N. G. Veselovskaya A. V. Ott O. V. Gritsenko EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS Кардиоваскулярная терапия и профилактика coronary atherosclerosis metabolic risk factors epicardial obesity |
| title | EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS |
| title_full | EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS |
| title_fullStr | EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS |
| title_full_unstemmed | EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS |
| title_short | EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS |
| title_sort | epicardial obesity and a range of metabolic risk factors relation with the prevalence index of coronary atherosclerosis |
| topic | coronary atherosclerosis metabolic risk factors epicardial obesity |
| url | https://cardiovascular.elpub.ru/jour/article/view/264 |
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