Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesis
Sugar signaling forms the basis of metabolic activities crucial for an organism to perform essential life activities. In plants, sugars like glucose, mediate a wide range of physiological responses ranging from seed germination to cell senescence. This has led to the elucidation of cell signaling pa...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
|
| Series: | Plant Signaling & Behavior |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/15592324.2024.2341506 |
| _version_ | 1797198530342813696 |
|---|---|
| author | Sanjay Singh Rawat Shital Sandhya Ashverya Laxmi |
| author_facet | Sanjay Singh Rawat Shital Sandhya Ashverya Laxmi |
| author_sort | Sanjay Singh Rawat |
| collection | DOAJ |
| description | Sugar signaling forms the basis of metabolic activities crucial for an organism to perform essential life activities. In plants, sugars like glucose, mediate a wide range of physiological responses ranging from seed germination to cell senescence. This has led to the elucidation of cell signaling pathways involving glucose and its counterparts and the mechanism of how these sugars take control over major hormonal pathways such as auxin, ethylene, abscisic acid and cytokinin in Arabidopsis. Plants use HXK1(Hexokinase) as a glucose sensor to modulate changes in photosynthetic gene expression in response to high glucose levels. Other proteins such as SIZ1, a major SUMO E3 ligase have recently been implicated in controlling sugar responses via transcriptional and translational regulation of a wide array of sugar metabolic genes. Here, we show that these two genes work antagonistically and are epistatic in controlling responsiveness toward high glucose conditions. |
| first_indexed | 2024-04-24T07:01:19Z |
| format | Article |
| id | doaj.art-c0538a932cd04add8cbb5efa6a01ac42 |
| institution | Directory Open Access Journal |
| issn | 1559-2316 1559-2324 |
| language | English |
| last_indexed | 2024-04-24T07:01:19Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Plant Signaling & Behavior |
| spelling | doaj.art-c0538a932cd04add8cbb5efa6a01ac422024-04-22T08:52:27ZengTaylor & Francis GroupPlant Signaling & Behavior1559-23161559-23242024-12-0119110.1080/15592324.2024.23415062341506Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesisSanjay Singh Rawat0Shital Sandhya1Ashverya Laxmi2National Institute of Plant Genome ResearchNational Institute of Plant Genome ResearchNational Institute of Plant Genome ResearchSugar signaling forms the basis of metabolic activities crucial for an organism to perform essential life activities. In plants, sugars like glucose, mediate a wide range of physiological responses ranging from seed germination to cell senescence. This has led to the elucidation of cell signaling pathways involving glucose and its counterparts and the mechanism of how these sugars take control over major hormonal pathways such as auxin, ethylene, abscisic acid and cytokinin in Arabidopsis. Plants use HXK1(Hexokinase) as a glucose sensor to modulate changes in photosynthetic gene expression in response to high glucose levels. Other proteins such as SIZ1, a major SUMO E3 ligase have recently been implicated in controlling sugar responses via transcriptional and translational regulation of a wide array of sugar metabolic genes. Here, we show that these two genes work antagonistically and are epistatic in controlling responsiveness toward high glucose conditions.http://dx.doi.org/10.1080/15592324.2024.2341506sugar signalingepistasishexokinase1post-germination growth arresthypocotyl |
| spellingShingle | Sanjay Singh Rawat Shital Sandhya Ashverya Laxmi Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesis Plant Signaling & Behavior sugar signaling epistasis hexokinase1 post-germination growth arrest hypocotyl |
| title | Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesis |
| title_full | Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesis |
| title_fullStr | Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesis |
| title_full_unstemmed | Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesis |
| title_short | Complex genetic interaction between glucose sensor HXK1 and E3 SUMO ligase SIZ1 in regulating plant morphogenesis |
| title_sort | complex genetic interaction between glucose sensor hxk1 and e3 sumo ligase siz1 in regulating plant morphogenesis |
| topic | sugar signaling epistasis hexokinase1 post-germination growth arrest hypocotyl |
| url | http://dx.doi.org/10.1080/15592324.2024.2341506 |
| work_keys_str_mv | AT sanjaysinghrawat complexgeneticinteractionbetweenglucosesensorhxk1ande3sumoligasesiz1inregulatingplantmorphogenesis AT shitalsandhya complexgeneticinteractionbetweenglucosesensorhxk1ande3sumoligasesiz1inregulatingplantmorphogenesis AT ashveryalaxmi complexgeneticinteractionbetweenglucosesensorhxk1ande3sumoligasesiz1inregulatingplantmorphogenesis |