The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in context
Summary: Background: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in SSA to inform health policy makers. Methods: We conducted a systematic review a...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | EClinicalMedicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589537023004327 |
| _version_ | 1797449440996360192 |
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| author | Maureen Moyo-Chilufya Kuhlula Maluleke Kabelo Kgarosi Monde Muyoyeta Charles Hongoro Alfred Musekiwa |
| author_facet | Maureen Moyo-Chilufya Kuhlula Maluleke Kabelo Kgarosi Monde Muyoyeta Charles Hongoro Alfred Musekiwa |
| author_sort | Maureen Moyo-Chilufya |
| collection | DOAJ |
| description | Summary: Background: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in SSA to inform health policy makers. Methods: We conducted a systematic review and meta-analysis on the prevalence of NCDs and risk factors among PLHIV in SSA. We comprehensively searched PubMed/MEDLINE, Scopus, and EBSCOhost (CINAHL) electronic databases for sources published from 2010 to July 2023. We applied the random effects meta-analysis model to pool the results using STATA. The systematic review protocol was registered on PROSPERO (registration number: CRD42021258769). Findings: We included 188 studies from 21 countries in this meta-analysis. Our findings indicate pooled prevalence estimates for hypertension (20.1% [95% CI:17.5–22.7]), depression (30.4% [25.3–35.4]), diabetes (5.4% [4.4–6.4]), cervical cancer (1.5% [0.1–2.9]), chronic respiratory diseases (7.1% [4.0–10.3]), overweight/obesity (32.2% [29.7–34.7]), hypercholesterolemia (21.3% [16.6–26.0]), metabolic syndrome (23.9% [19.5–28.7]), alcohol consumption (21.3% [17.9–24.6]), and smoking (6.4% [5.2–7.7]). Interpretation: People living with HIV have a high prevalence of NCDs and their risk factors including hypertension, depression, overweight/obesity, hypercholesterolemia, metabolic syndrome and alcohol consumption. We recommend strengthening of health systems to allow for improved integration of NCDs and HIV services in public health facilities in SSA. NCD risk factors such as obesity, hypercholesterolemia, and alcohol consumption can be addressed through health promotion campaigns. There is a need for further research on the burden of NCDs among PLHIV in most of SSA. Funding: This study did not receive any funding. |
| first_indexed | 2024-03-09T14:26:05Z |
| format | Article |
| id | doaj.art-c053efe970e5479491942a003ce2689c |
| institution | Directory Open Access Journal |
| issn | 2589-5370 |
| language | English |
| last_indexed | 2024-03-09T14:26:05Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | EClinicalMedicine |
| spelling | doaj.art-c053efe970e5479491942a003ce2689c2023-11-28T07:26:42ZengElsevierEClinicalMedicine2589-53702023-11-0165102255The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in contextMaureen Moyo-Chilufya0Kuhlula Maluleke1Kabelo Kgarosi2Monde Muyoyeta3Charles Hongoro4Alfred Musekiwa5Faculty of Health Sciences, School of Health Systems and Public Health, University of Pretoria, Pretoria, South AfricaFaculty of Health Sciences, School of Health Systems and Public Health, University of Pretoria, Pretoria, South AfricaFaculty of Health Sciences, School of Health Systems and Public Health, University of Pretoria, Pretoria, South AfricaCentre for Infectious Disease Research in Zambia, Lusaka, ZambiaFaculty of Health Sciences, School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa; Human Sciences Research Council, Pretoria, South AfricaFaculty of Health Sciences, School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa; Corresponding author. Faculty of Health Sciences, 31 Room 5-10, Level 5, HW Snyman Building (North), Bophelo Road, Gezina, Pretoria 0084, South Africa.Summary: Background: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in SSA to inform health policy makers. Methods: We conducted a systematic review and meta-analysis on the prevalence of NCDs and risk factors among PLHIV in SSA. We comprehensively searched PubMed/MEDLINE, Scopus, and EBSCOhost (CINAHL) electronic databases for sources published from 2010 to July 2023. We applied the random effects meta-analysis model to pool the results using STATA. The systematic review protocol was registered on PROSPERO (registration number: CRD42021258769). Findings: We included 188 studies from 21 countries in this meta-analysis. Our findings indicate pooled prevalence estimates for hypertension (20.1% [95% CI:17.5–22.7]), depression (30.4% [25.3–35.4]), diabetes (5.4% [4.4–6.4]), cervical cancer (1.5% [0.1–2.9]), chronic respiratory diseases (7.1% [4.0–10.3]), overweight/obesity (32.2% [29.7–34.7]), hypercholesterolemia (21.3% [16.6–26.0]), metabolic syndrome (23.9% [19.5–28.7]), alcohol consumption (21.3% [17.9–24.6]), and smoking (6.4% [5.2–7.7]). Interpretation: People living with HIV have a high prevalence of NCDs and their risk factors including hypertension, depression, overweight/obesity, hypercholesterolemia, metabolic syndrome and alcohol consumption. We recommend strengthening of health systems to allow for improved integration of NCDs and HIV services in public health facilities in SSA. NCD risk factors such as obesity, hypercholesterolemia, and alcohol consumption can be addressed through health promotion campaigns. There is a need for further research on the burden of NCDs among PLHIV in most of SSA. Funding: This study did not receive any funding.http://www.sciencedirect.com/science/article/pii/S2589537023004327Non-communicable diseasesPeople living with HIVSub-Saharan AfricaHIV/AIDSSystematic reviewMeta-analysis |
| spellingShingle | Maureen Moyo-Chilufya Kuhlula Maluleke Kabelo Kgarosi Monde Muyoyeta Charles Hongoro Alfred Musekiwa The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in context EClinicalMedicine Non-communicable diseases People living with HIV Sub-Saharan Africa HIV/AIDS Systematic review Meta-analysis |
| title | The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in context |
| title_full | The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in context |
| title_fullStr | The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in context |
| title_full_unstemmed | The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in context |
| title_short | The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysisResearch in context |
| title_sort | burden of non communicable diseases among people living with hiv in sub saharan africa a systematic review and meta analysisresearch in context |
| topic | Non-communicable diseases People living with HIV Sub-Saharan Africa HIV/AIDS Systematic review Meta-analysis |
| url | http://www.sciencedirect.com/science/article/pii/S2589537023004327 |
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