Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa

We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008–April 2009, 13 (68%) had isolates resistant to all 8 drugs tes...

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Main Authors: N. Sarita Shah, Jessica Richardson, Prashini Moodley, Salona Moodley, Palav Babaria, Melissa Ramtahal, Scott K. Heysell, Xuan Li, Anthony P. Moll, Gerald Friedland, A. Willem Sturm, Neel R. Gandhi
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2011-03-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/17/3/10-1363_article
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author N. Sarita Shah
Jessica Richardson
Prashini Moodley
Salona Moodley
Palav Babaria
Melissa Ramtahal
Scott K. Heysell
Xuan Li
Anthony P. Moll
Gerald Friedland
A. Willem Sturm
Neel R. Gandhi
author_facet N. Sarita Shah
Jessica Richardson
Prashini Moodley
Salona Moodley
Palav Babaria
Melissa Ramtahal
Scott K. Heysell
Xuan Li
Anthony P. Moll
Gerald Friedland
A. Willem Sturm
Neel R. Gandhi
author_sort N. Sarita Shah
collection DOAJ
description We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008–April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.
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spelling doaj.art-c0556da7753d4705b3d1c9678b3fe93b2022-12-21T18:58:59ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592011-03-0117351051310.3201/eid1703.101363Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South AfricaN. Sarita ShahJessica RichardsonPrashini MoodleySalona MoodleyPalav BabariaMelissa RamtahalScott K. HeysellXuan LiAnthony P. MollGerald FriedlandA. Willem SturmNeel R. GandhiWe expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008–April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.https://wwwnc.cdc.gov/eid/article/17/3/10-1363_articleExtensively drug-resistant tuberculosistuberculosis and other mycobacteriaHIVdrug resistancesecond-line drugsSouth Africa
spellingShingle N. Sarita Shah
Jessica Richardson
Prashini Moodley
Salona Moodley
Palav Babaria
Melissa Ramtahal
Scott K. Heysell
Xuan Li
Anthony P. Moll
Gerald Friedland
A. Willem Sturm
Neel R. Gandhi
Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
Emerging Infectious Diseases
Extensively drug-resistant tuberculosis
tuberculosis and other mycobacteria
HIV
drug resistance
second-line drugs
South Africa
title Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_full Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_fullStr Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_full_unstemmed Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_short Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_sort increasing drug resistance in extensively drug resistant tuberculosis south africa
topic Extensively drug-resistant tuberculosis
tuberculosis and other mycobacteria
HIV
drug resistance
second-line drugs
South Africa
url https://wwwnc.cdc.gov/eid/article/17/3/10-1363_article
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