Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients

Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients

Abstract Lymph nodes (LNs) and distant metastases can arise from independent subclones of the primary tumor. Herein, we characterized the molecular landscape and the differences between LNs, distant metastases and primary colorectal cancers (CRCs). Samples were analyzed using next generation sequenc...

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Detalles Bibliográficos
Main Authors: Alberto Puccini, Andreas Seeber, Joanne Xiu, Richard M. Goldberg, Davide Soldato, Axel Grothey, Anthony F. Shields, Mohamed E. Salem, Francesca Battaglin, Martin D. Berger, Wafik S. El-Deiry, Ryuma Tokunaga, Madiha Naseem, Wu Zhang, Sukeshi Patel Arora, Moh’d M. Khushman, Michael J. Hall, Philip A. Philip, John L. Marshall, W. Michael Korn, Heinz-Josef Lenz
Formato: Artigo
Idioma:English
Publicado: Nature Portfolio 2021-10-01
Series:npj Precision Oncology
Acceso en liña:https://doi.org/10.1038/s41698-021-00230-y

Internet

https://doi.org/10.1038/s41698-021-00230-y

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