SUV39H1 is a novel biomarker targeting oxidative phosphorylation in hepatitis B virus-associated hepatocellular carcinoma

SUV39H1 is a novel biomarker targeting oxidative phosphorylation in hepatitis B virus-associated hepatocellular carcinoma

Abstract Background As a histone methyltransferase, suppressor of variegation 3–9 homolog 1 (SUV39H1) plays an important role in the occurrence and development of cancer. To explore the mechanism and biological function of SUV39H1 in hepatitis B virus-associated hepatocellular carcinoma (HBV-HCC) ca...

Full description

Bibliographic Details
Main Authors:	Yanping Zhang, Wanwen Lao, Kaming Yang, Xinyi Kong, Yuetong Li, Xin Yu, Xumeng Wang, Yang Liu, Zhenlin Li, Yilin Deng, Shuping Nie, Changlong Bi, Chao Wu, Aixia Zhai
Format:	Article
Language:	English
Published:	BMC 2023-11-01
Series:	BMC Cancer
Subjects:	SUV39H1 Hepatocellular carcinoma Hepatitis B virus Oxidative phosphorylation Biomarker
Online Access:	https://doi.org/10.1186/s12885-023-11633-4

Similar Items

H3K9 Methyltransferases Suv39h1 and Suv39h2 Control the Differentiation of Neural Progenitor Cells in the Adult Hippocampus
by: Miguel V. Guerra, et al.
Published: (2022-01-01)

The histone methyltransferase Suv39h regulates 3T3-L1 adipogenesis
by: Jia Jing, et al.
Published: (2020-01-01)

RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin
by: Whitney L Johnson, et al.
Published: (2017-08-01)

Identification of Differentially Methylated Regions Associated with a Knockout of SUV39H1 in Prostate Cancer Cells
by: Wenbo Yan, et al.
Published: (2020-10-01)

Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation
by: Oscar Velazquez Camacho, et al.
Published: (2017-08-01)

Regulation of the SUV39H Family Methyltransferases: Insights from Fission Yeast
by: Rinko Nakamura, et al.
Published: (2023-03-01)

Histone methyltransferase SUV39H2 regulates cell growth and chemosensitivity in glioma via regulation of hedgehog signaling
by: Ran Wang, et al.
Published: (2019-10-01)

Targeting FBXO44/SUV39H1 elicits tumor cell-specific DNA replication stress and viral mimicry
by: Jia Z. Shen, et al.
Published: (2021-02-01)

Inhibition of SUV39H1 reduces tumor angiogenesis via Notch1 in oral squamous cell carcinoma
by: Yan Chen, et al.
Published: (2024-04-01)

SUV39H1 deficiency suppresses clear cell renal cell carcinoma growth by inducing ferroptosis
by: Jianfeng Wang, et al.
Published: (2021-02-01)

PHF6 functions as a tumor suppressor by recruiting methyltransferase SUV39H1 to nucleolar region and offers a novel therapeutic target for PHF6-muntant leukemia
by: Hsiang-i Tsai, et al.
Published: (2022-04-01)

Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly
by: Atsuko Shirai, et al.
Published: (2017-08-01)

SUV39H1 regulates corneal epithelial wound healing via H3K9me3-mediated repression of p27
by: Shuai Yang, et al.
Published: (2022-02-01)

SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer
by: Li Zhang, et al.
Published: (2020-07-01)

Interobserver variability of image-derived arterial blood SUV in whole-body FDG PET
by: Frank Hofheinz, et al.
Published: (2019-03-01)

USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation
by: Sathish Kumar Mungamuri, et al.
Published: (2016-03-01)

LncRNA HOTAIR promotes the proliferation and invasion/metastasis of breast cancer cells by targeting the miR-130a-3p/Suv39H1 axis
by: Wenxing He, et al.
Published: (2022-07-01)

An HP1 isoform-specific feedback mechanism regulates Suv39h1 activity under stress conditions
by: Helena Raurell-Vila, et al.
Published: (2017-02-01)

Effect of SUV39H1 Histone Methyltransferase Knockout on Expression of Differentiation-Associated Genes in HaCaT Keratinocytes
by: Barbara Sobiak, et al.
Published: (2020-12-01)

Effect of Tumor-Pixel Positioning on the Variability of SUV Measurements in PET Images
by: Koji Itagaki, et al.
Published: (2023-01-01)

Analysis and Optimization of SUV Drive Axle Abnormal Sound
by: Lü Chenming, et al.
Published: (2018-01-01)

Lactobacillus gasseri LA39 Activates the Oxidative Phosphorylation Pathway in Porcine Intestinal Epithelial Cells
by: Jun Hu, et al.
Published: (2018-12-01)

SUV3 Helicase and Mitochondrial Homeostasis
by: Phang-Lang Chen
Published: (2023-05-01)

Evaluation of SUV normalized by lean body mass (SUL) in 68Ga-PSMA11 PET/CT: a bi-centric analysis
by: Andrei Gafita, et al.
Published: (2019-12-01)

The SUV4-20H Histone Methyltransferases in Health and Disease
by: Davide Gabellini, et al.
Published: (2022-04-01)

Suppressor of variegation 3–9 homologue 1 impairment and neutrophil-skewed systemic inflammation are associated with comorbidities in COPD
by: Tzu-Tao Chen, et al.
Published: (2021-10-01)

Clinical use of Ortho-SUV transosseous hexapod in treatment of lower limb false joints
by: N. V. Tishkov, et al.
Published: (2016-07-01)

Exploration of the threshold SUV for diagnosis of malignancy using 18F-FBPA PET/CT
by: Kayako Isohashi, et al.
Published: (2022-12-01)

RBM39 Alters Phosphorylation of c-Jun and Binds to Viral RNA to Promote PRRSV Proliferation
by: Yinna Song, et al.
Published: (2021-05-01)

When SUV Matters: FDG PET/CT at Baseline Correlates with Survival in Soft Tissue and Ewing Sarcoma
by: Ruben I. Hack, et al.
Published: (2021-08-01)

Monitoring scanner calibration using the image-derived arterial blood SUV in whole-body FDG-PET
by: Jens Maus, et al.
Published: (2018-05-01)

Rapid Standardized CT-Based Method to Determine Lean Body Mass SUV for PET—A Significant Improvement Over Prediction Equations
by: Terence A. Riauka, et al.
Published: (2022-07-01)

Multicentre analysis of PET SUV using vendor-neutral software: the Japanese Harmonization Technology (J-Hart) study
by: Yuji Tsutsui, et al.
Published: (2018-08-01)

Use of a digital phantom developed by QIBA for harmonizing SUVs obtained from the state-of-the-art SPECT/CT systems: a multicenter study
by: Tadaki Nakahara, et al.
Published: (2017-06-01)

CXCL8, CXCL9, CXCL10, and CXCL11 as biomarkers of liver injury caused by chronic hepatitis B
by: Xin Yu, et al.
Published: (2022-11-01)

Baseline SUV Range for Liver and Blood Pool in Patients Undergoing F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
by: Yasemin Parlak, et al.
Published: (2019-09-01)

FDG-PET Response Prediction in Pediatric Hodgkin’s Lymphoma: Impact of Metabolically Defined Tumor Volumes and Individualized SUV Measurements on the Positive Predictive Value
by: Amr Elsayed M. Hussien, et al.
Published: (2015-01-01)

Taylor spatial frame versus ortho SUV for correction of lower limb deformities: A comparative study
by: Manish Dhawan, et al.
Published: (2023-01-01)

What and how should we measure in paediatric oncology FDG-PET/CT? Comparison of commonly used SUV metrics for differentiation between paediatric tumours
by: Janusch Blautzik, et al.
Published: (2019-12-01)

Comparison of standardized uptake values between 99mTc-HDP SPECT/CT and 18F-NaF PET/CT in bone metastases of breast and prostate cancer
by: Samuli Arvola, et al.
Published: (2019-01-01)