The Effects of PP2A Disruption on ER-Mitochondria Contact and Mitochondrial Functions in Neuronal-like Cells

The Effects of PP2A Disruption on ER-Mitochondria Contact and Mitochondrial Functions in Neuronal-like Cells

Mitochondria-associated membranes (MAMs) regulate several cellular processes, including calcium homeostasis and mitochondrial function, and dynamics. While MAMs are upregulated in Alzheimer’s disease (AD), the mechanisms underlying this increase remain unknown. A possible mechanism may include dysre...

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Bibliographic Details
Main Authors: Phaewa Chaiwijit, Kwanchanok Uppakara, Nithi Asavapanumas, Witchuda Saengsawang
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
PP2A
ER-mitochondria contacts
MAMs
calcium
mitochondrial dynamics
Alzheimer’s disease
Online Access:https://www.mdpi.com/2227-9059/11/4/1011

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