Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析)
研究了用毛细管胶束电动色谱快速测定解热镇痛药复方阿司匹林(APC)中阿司匹林(AS)、非那西丁(PH)、咖啡因(CA)及复方扑热息痛(PAC)中扑热息痛(PA)，AS，CA含量的方法.使用长37 cm（有效长度30 cm）内径75 µm的石英毛细管，+ 20kV分离电压，在pH 8.65的9 mmol · L-1 Na2B4O7-13 mmol • L-1 KH2PO4 （内含60 mmol · L-1 SDS和2%乙醇）缓冲溶液中，同一制剂中的三组分可在4.5 min内完全分离.用紫外检测器在214 nm处检测，外标法定量.测定4组分的相对标准偏差在0.84%~1.84%之间，回收率在99%...
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| Format: | Article |
| Language: | zho |
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Zhejiang University Press
2001-07-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
| Subjects: | |
| Online Access: | https://doi.org/zjup/1008-9497.2001.28.4.417-422 |
| _version_ | 1797236514834350080 |
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| author | CAIZeng-xuan(蔡增轩) CHENHeng-wu(陈恒武) |
| author_facet | CAIZeng-xuan(蔡增轩) CHENHeng-wu(陈恒武) |
| author_sort | CAIZeng-xuan(蔡增轩) |
| collection | DOAJ |
| description | 研究了用毛细管胶束电动色谱快速测定解热镇痛药复方阿司匹林(APC)中阿司匹林(AS)、非那西丁(PH)、咖啡因(CA)及复方扑热息痛(PAC)中扑热息痛(PA)，AS，CA含量的方法.使用长37 cm（有效长度30 cm）内径75 µm的石英毛细管，+ 20kV分离电压，在pH 8.65的9 mmol · L-1 Na2B4O7-13 mmol • L-1 KH2PO4 （内含60 mmol · L-1 SDS和2%乙醇）缓冲溶液中，同一制剂中的三组分可在4.5 min内完全分离.用紫外检测器在214 nm处检测，外标法定量.测定4组分的相对标准偏差在0.84%~1.84%之间，回收率在99%~104%之间.所建立的方法应用于复方阿司匹林片和复方扑热息痛片的成分分析，结果令人满意. |
| first_indexed | 2024-04-24T17:05:04Z |
| format | Article |
| id | doaj.art-c0626f0e539b40f6b84d5c2a2d2be1b7 |
| institution | Directory Open Access Journal |
| issn | 1008-9497 |
| language | zho |
| last_indexed | 2024-04-24T17:05:04Z |
| publishDate | 2001-07-01 |
| publisher | Zhejiang University Press |
| record_format | Article |
| series | Zhejiang Daxue xuebao. Lixue ban |
| spelling | doaj.art-c0626f0e539b40f6b84d5c2a2d2be1b72024-03-29T01:58:17ZzhoZhejiang University PressZhejiang Daxue xuebao. Lixue ban1008-94972001-07-01284417422zjup/1008-9497.2001.28.4.417-422Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析)CAIZeng-xuan(蔡增轩)0CHENHeng-wu(陈恒武)1Department of Chemistry, Zhejiang University, Hangzhou 310028, China(浙江大学化学系，浙江 杭州 310028)Department of Chemistry, Zhejiang University, Hangzhou 310028, China(浙江大学化学系，浙江 杭州 310028)研究了用毛细管胶束电动色谱快速测定解热镇痛药复方阿司匹林(APC)中阿司匹林(AS)、非那西丁(PH)、咖啡因(CA)及复方扑热息痛(PAC)中扑热息痛(PA)，AS，CA含量的方法.使用长37 cm（有效长度30 cm）内径75 µm的石英毛细管，+ 20kV分离电压，在pH 8.65的9 mmol · L-1 Na2B4O7-13 mmol • L-1 KH2PO4 （内含60 mmol · L-1 SDS和2%乙醇）缓冲溶液中，同一制剂中的三组分可在4.5 min内完全分离.用紫外检测器在214 nm处检测，外标法定量.测定4组分的相对标准偏差在0.84%~1.84%之间，回收率在99%~104%之间.所建立的方法应用于复方阿司匹林片和复方扑热息痛片的成分分析，结果令人满意.https://doi.org/zjup/1008-9497.2001.28.4.417-422毛细管胶束电动色谱阿司匹林扑热息痛非那西丁咖啡因定量分析 |
| spellingShingle | CAIZeng-xuan(蔡增轩) CHENHeng-wu(陈恒武) Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析) Zhejiang Daxue xuebao. Lixue ban 毛细管胶束电动色谱 阿司匹林 扑热息痛 非那西丁 咖啡因 定量分析 |
| title | Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析) |
| title_full | Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析) |
| title_fullStr | Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析) |
| title_full_unstemmed | Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析) |
| title_short | Fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography(复方解热镇痛药的毛细管胶束电动色谱快速分析) |
| title_sort | fast determination of active ingredients in compound antipyretic analgesic tablets by micellar electrokinetic capillary chromatography 复方解热镇痛药的毛细管胶束电动色谱快速分析 |
| topic | 毛细管胶束电动色谱 阿司匹林 扑热息痛 非那西丁 咖啡因 定量分析 |
| url | https://doi.org/zjup/1008-9497.2001.28.4.417-422 |
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