Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis
Purpose: To assess the corneal endothelium in patients with Fuchs heterochromic iridocyclitis (FHI) and compare it with the normal fellow eye. Methods: Retrospective, observational, cross-sectional study of 31 patients seen between Jan 2016 to Dec 2018, with clinical diagnosis of Fuchs heterochromic...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=447;epage=449;aulast=Sravani |
| _version_ | 1819146358725017600 |
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| author | N Geetha Sravani Ashik Mohamed Sunita Chaurasia Shravya Sri Durgam Somasheila I Murthy |
| author_facet | N Geetha Sravani Ashik Mohamed Sunita Chaurasia Shravya Sri Durgam Somasheila I Murthy |
| author_sort | N Geetha Sravani |
| collection | DOAJ |
| description | Purpose: To assess the corneal endothelium in patients with Fuchs heterochromic iridocyclitis (FHI) and compare it with the normal fellow eye. Methods: Retrospective, observational, cross-sectional study of 31 patients seen between Jan 2016 to Dec 2018, with clinical diagnosis of Fuchs heterochromic iridocyclitis, was performed. Specular microscopic examination was documented in both eyes. The affected eyes formed the study group and the fellow healthy eyes served as controls. Results: The mean age of the patients was 29.9 ± 8.2 years. The endothelial cell density (P = 0.0001) was significantly lower, whereas average cell size (P = 0.0001), coefficient of variation (P = 0.004), and maximum cell area (P = 0.01) were significantly higher in the affected eye compared to the control eye. In three patients, the affected eye showed guttae, while the healthy fellow eye revealed a normal specular mosaic. Conclusion: Specular microscopic analysis shows endothelial alterations in the affected eyes in FHI. |
| first_indexed | 2024-12-22T13:12:40Z |
| format | Article |
| id | doaj.art-c06516a7afe44c6e89ab05502b55d34d |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-22T13:12:40Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-c06516a7afe44c6e89ab05502b55d34d2022-12-21T18:24:43ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-0168344744910.4103/ijo.IJO_869_19Corneal endothelium in unilateral Fuchs heterochromic iridocyclitisN Geetha SravaniAshik MohamedSunita ChaurasiaShravya Sri DurgamSomasheila I MurthyPurpose: To assess the corneal endothelium in patients with Fuchs heterochromic iridocyclitis (FHI) and compare it with the normal fellow eye. Methods: Retrospective, observational, cross-sectional study of 31 patients seen between Jan 2016 to Dec 2018, with clinical diagnosis of Fuchs heterochromic iridocyclitis, was performed. Specular microscopic examination was documented in both eyes. The affected eyes formed the study group and the fellow healthy eyes served as controls. Results: The mean age of the patients was 29.9 ± 8.2 years. The endothelial cell density (P = 0.0001) was significantly lower, whereas average cell size (P = 0.0001), coefficient of variation (P = 0.004), and maximum cell area (P = 0.01) were significantly higher in the affected eye compared to the control eye. In three patients, the affected eye showed guttae, while the healthy fellow eye revealed a normal specular mosaic. Conclusion: Specular microscopic analysis shows endothelial alterations in the affected eyes in FHI.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=447;epage=449;aulast=Sravanicorneal endotheliumfuchs heterochromic iridocyclitisspecular microscopy |
| spellingShingle | N Geetha Sravani Ashik Mohamed Sunita Chaurasia Shravya Sri Durgam Somasheila I Murthy Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis Indian Journal of Ophthalmology corneal endothelium fuchs heterochromic iridocyclitis specular microscopy |
| title | Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis |
| title_full | Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis |
| title_fullStr | Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis |
| title_full_unstemmed | Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis |
| title_short | Corneal endothelium in unilateral Fuchs heterochromic iridocyclitis |
| title_sort | corneal endothelium in unilateral fuchs heterochromic iridocyclitis |
| topic | corneal endothelium fuchs heterochromic iridocyclitis specular microscopy |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=447;epage=449;aulast=Sravani |
| work_keys_str_mv | AT ngeethasravani cornealendotheliuminunilateralfuchsheterochromiciridocyclitis AT ashikmohamed cornealendotheliuminunilateralfuchsheterochromiciridocyclitis AT sunitachaurasia cornealendotheliuminunilateralfuchsheterochromiciridocyclitis AT shravyasridurgam cornealendotheliuminunilateralfuchsheterochromiciridocyclitis AT somasheilaimurthy cornealendotheliuminunilateralfuchsheterochromiciridocyclitis |