Stereoselective Synthesis of the I–L Fragment of the Pacific Ciguatoxins

The I–L ring system found in all the Pacific ciguatoxins has been prepared from a tricyclic precursor in a highly stereoselective manner. Subtle differences in the reactivity of the enones present in the seven- and eight-membered rings of the tricyclic ether starting material have been exploited to...

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Bibliographic Details
Main Authors: J. Stephen Clark, Michael Popadynec
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/12/740