Endurance Exercise Attenuates Established Progressive Experimental Autoimmune Encephalomyelitis and Is Associated with an Amelioration of Innate Immune Responses in NOD Mice

Endurance Exercise Attenuates Established Progressive Experimental Autoimmune Encephalomyelitis and Is Associated with an Amelioration of Innate Immune Responses in NOD Mice

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease causing axonal degeneration and demyelination. Exercise in mice with active monophasic experimental autoimmune encephalomyelitis (EAE) attenuates disease severity associated with diverse impacts on T cell-mediated immunity. However...

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Bibliographic Details
Main Authors: Daniel Schiffmann, Victoria Lampkemeyer, Maren Lindner, Ann-Katrin Fleck, Kathrin Koch, Melanie Eschborn, Marie Liebmann, Jan-Kolja Strecker, Jens Minnerup, Heinz Wiendl, Luisa Klotz
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
experimental autoimmune encephalomyelitis
multiple sclerosis
autoimmunity
central nervous system
exercise
lifestyle intervention
Online Access:https://www.mdpi.com/1422-0067/24/21/15798

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