Study of correlation between imatinib mesylate plasma levels and hematological profile of patients undergoing treatment for chronic myeloid leukemia

Study of correlation between imatinib mesylate plasma levels and hematological profile of patients undergoing treatment for chronic myeloid leukemia

ABSTRACT Introdution: Chronic myeloid leukemia (CML) is a genetic disorder of hematopoietic stem cells, resulting in a myeloproliferative expansion of blood cells. CML is associated with the presence of the Philadelphia chromosome (Ph), generating an oncogene (BCR-ABL). The current treatment of cho...

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Bibliographic Details
Main Authors: Emanuelle S. Dal Ponte, Sandrine C. Wagner, Rafael Linden, Helena Schirmer
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2017-06-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
chronic myeloid leukemia
imatinib mesylate
tyrosine kinase inhibitor
treatment outcome
Online Access:http://www.scielo.br/pdf/jbpml/v53n3/1676-2444-jbpml-53-03-0159.pdf

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