Type 2 Immunity and Its Impact on COVID-19 Infection in the Airways

Type 2 Immunity and Its Impact on COVID-19 Infection in the Airways

Type 2 immune responses are characterized by elevated type 2 cytokines and blood eosinophilia. Emerging evidence suggests that people with chronic type 2 inflammatory lung diseases are not particularly susceptible to SARS-CoV-2 infection. Intriguingly, recent in vitro, ex vivo research demonstrates...

Full description

Bibliographic Details
Main Authors:	Prabuddha S. Pathinayake, Nikhil T. Awatade, Peter A. B. Wark
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	Viruses
Subjects:	COVID-19 SARS-CoV-2 type 2 immunity airway epithelium asthma M2 macrophages
Online Access:	https://www.mdpi.com/1999-4915/15/2/402

Similar Items

Inhibition of SARS-CoV-2 infection in human airway epithelium with a xeno-nucleic acid aptamer
by: Niayesh Razi, et al.
Published: (2023-11-01)

The interplay between the airway epithelium and tissue macrophages during the SARS-CoV-2 infection
by: Emilia Barreto-Duran, et al.
Published: (2022-10-01)

SARS-CoV-2 infection increases airway bleeding risk in patients after tracheostomies
by: Shupin Tang, et al.
Published: (2024-03-01)

Characterization of the SARS-CoV-2 Host Response in Primary Human Airway Epithelial Cells from Aged Individuals
by: Bharathiraja Subramaniyan, et al.
Published: (2021-08-01)

Up-regulation of ACE2, the SARS-CoV-2 receptor, in asthmatics on maintenance inhaled corticosteroids
by: Sarah L. O’Beirne, et al.
Published: (2021-07-01)

Broad antiviral and anti‐inflammatory efficacy of nafamostat against SARS‐CoV‐2 and seasonal coronaviruses in primary human bronchiolar epithelia
by: Brian F. Niemeyer, et al.
Published: (2022-02-01)

Involvement of Oxidative Stress and the Innate Immune System in SARS-CoV-2 Infection
by: Evgenii M. Kozlov, et al.
Published: (2021-02-01)

Long-Term Modeling of SARS-CoV-2 Infection of <italic toggle="yes">In Vitro</italic> Cultured Polarized Human Airway Epithelium
by: Siyuan Hao, et al.
Published: (2020-12-01)

Airway Remodeling in Asthma
by: Kenneth P. Hough, et al.
Published: (2020-05-01)

Altered COVID-19 immunity in children with asthma by atopic status
by: Sherry Tong, BS, et al.
Published: (2024-05-01)

Eye Infection with SARS-CoV-2 as a Route to Systemic Immunization?
by: Norbert Schrage, et al.
Published: (2022-06-01)

Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium
by: Silva Kasela, et al.
Published: (2021-04-01)

Epigenetic Regulation of Airway Epithelium Immune Functions in Asthma
by: Bilal Alashkar Alhamwe, et al.
Published: (2020-08-01)

IMMUNE RESPONSE TO SARS-COV-2 IN PATIENTS WITH CHRONIC HIV INFECTION
by: Damian Vangelov, et al.
Published: (2023-08-01)

Inactivation of Material from SARS-CoV-2-Infected Primary Airway Epithelial Cell Cultures
by: Kaitlyn A. Barrow, et al.
Published: (2021-01-01)

Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD
by: Narjes Saheb Sharif-Askari, et al.
Published: (2020-09-01)

The impact of helminth-induced immunity on infection with bacteria or viruses
by: Hong Chen, et al.
Published: (2023-10-01)

Protective action of natural and induced immunization against the occurrence of delta or alpha variants of SARS-CoV-2 infection: a test-negative case-control study
by: Giovanni Corrao, et al.
Published: (2022-02-01)

The immune mechanism of the nasal epithelium in COVID-19–related olfactory dysfunction
by: Shunmei Chen, et al.
Published: (2023-07-01)

Airway Epithelial Innate Immunity
by: Sebastian L. Johnston, et al.
Published: (2021-11-01)

Airway Epithelium: A Neglected but Crucial Cell Type in Asthma Pathobiology
by: Sabita Singh, et al.
Published: (2023-02-01)

Apical-Out Human Airway Organoids Modeling SARS-CoV-2 Infection
by: Man Chun Chiu, et al.
Published: (2023-05-01)

ColdZyme Maintains Integrity in SARS-CoV-2-Infected Airway Epithelia
by: W. Posch, et al.
Published: (2021-04-01)

Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection
by: Yanwen Liang, et al.
Published: (2020-05-01)

Effect of Angiotensin-Converting-Enzyme Inhibitor and Angiotensin II Receptor Antagonist Treatment on ACE2 Expression and SARS-CoV-2 Replication in Primary Airway Epithelial Cells
by: Oghenemega Okoloko, et al.
Published: (2021-11-01)

An Update on Innate Immune Responses during SARS-CoV-2 Infection
by: Yu Zhang, et al.
Published: (2021-10-01)

SARS-CoV-2 Breakthrough Infections According to the Immune Response Elicited after mRNA Third Dose Vaccination in COVID-19-Naïve Hospital Personnel
by: Annapaola Santoro, et al.
Published: (2023-04-01)

SARS-CoV-2 infection aggravates cigarette smoke-exposed cell damage in primary human airway epithelia
by: Rui Chen, et al.
Published: (2023-04-01)

Enrichment of SARS-CoV-2 Entry Factors and Interacting Intracellular Genes in Tissue and Circulating Immune Cells
by: Abhinandan Devaprasad, et al.
Published: (2021-09-01)

SARS-CoV2 Infection During Pregnancy Causes Persistent Immune Abnormalities in Women Without Affecting the Newborns
by: Elena Vazquez-Alejo, et al.
Published: (2022-07-01)

A Diagnostic Strategy for Gauging Individual Humoral Ex Vivo Immune Responsiveness Following COVID-19 Vaccination
by: Anna Sabrina Kuechler, et al.
Published: (2022-06-01)

Immune response in SARS-CoV-2 infection: the role of interferons type I and type III
by: Caciane Portela Sousa, et al.
Published: (2020-09-01)

Mucosal Immunity against SARS-CoV-2 in the Respiratory Tract
by: Hae-Eun Noh, et al.
Published: (2024-01-01)

SARS-CoV-2 infection: Understanding the immune system abnormalities to get an adequate diagnosis
by: Karen Medina-Quero, et al.
Published: (2021-10-01)

Inflammatory and Immune Responses during SARS-CoV-2 Infection in Vaccinated and Non-Vaccinated Pregnant Women and Their Newborns
by: Paola Zelini, et al.
Published: (2023-04-01)

Current Recommendations for Airway Management Techniques in COVID-19 Patients without Respiratory Failure Undergoing General Anaesthesia: A Nonsystematic Literature Review
by: Milda Grigonytė, et al.
Published: (2021-02-01)

Long-Term Humoral Immune Response against SARS-CoV-2 after Natural Infection and Subsequent Vaccination According to WHO International Binding Antibody Units (BAU/mL)
by: Natalia Ruetalo, et al.
Published: (2021-11-01)

SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site
by: Anna Z Mykytyn, et al.
Published: (2021-01-01)

SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD – Possible Implications for Interstitial Fibrosis
by: Brake SJ, et al.
Published: (2022-01-01)

Quantitative Analysis of SARS-CoV-2 Serological Responses Post Three Doses of Immunization and Prior to Breakthrough COVID-19 Infections
by: Kathryn Macrae, et al.
Published: (2022-09-01)