Fine-Tuning of iPSC Derivation by an Inducible Reprogramming System at the Protein Level

Fine-Tuning of iPSC Derivation by an Inducible Reprogramming System at the Protein Level

Induced pluripotent stem cells (iPSCs) generated from somatic cells by ectopic expression of reprogramming factors, e.g., POU5F1 (OCT4), KLF4, and SOX2, have great potential for regenerative medicine. However, before they can be used in a clinical setting, the mechanism of reprogramming needs to be...

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Bibliographic Details
Main Authors: Dandan Sui, Zhaolin Sun, Chunlong Xu, Yuanyuan Wu, Mario R. Capecchi, Sen Wu, Ning Li
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114000927

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