Molecular Epidemiology of Human Intestinal Amoebas in Iran

Many microscopic-based epidemiological surveys on the prevalence of human intestinal pathogenic and non-pathogenic protozoa including intestinal amoeba performed in Iran show a high prevalence of human intestinal amoeba in different parts of Iran. Such epidemiological studies on amoebiasis are confu...

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Main Authors: H Hooshyar, P Rostamkhani, M Rezaian
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2012-09-01
Series:Iranian Journal of Public Health
Subjects:
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/2511
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author H Hooshyar
P Rostamkhani
M Rezaian
author_facet H Hooshyar
P Rostamkhani
M Rezaian
author_sort H Hooshyar
collection DOAJ
description Many microscopic-based epidemiological surveys on the prevalence of human intestinal pathogenic and non-pathogenic protozoa including intestinal amoeba performed in Iran show a high prevalence of human intestinal amoeba in different parts of Iran. Such epidemiological studies on amoebiasis are confusing, mainly due to recently appreciated distinction between the Entamoeba histolytica, E. dispar and E. moshkovskii. Differential diagnosis can be done by some methods such as PCR-based methods, monoclonal antibodies and the analysis of isoenzyme typing, however the molecular study of these protozoa in Iran is low. Based on molecular studies, it seems that E. dispar is predominant species especially in the central and northern areas of Iran and amoebiasis due to E. histolytica is a rare infection in the country. It is suggested that infection with E. moshkovskii may be common among Iranians. Considering the importance of molecular epidemiology of amoeba in Iran and also the current data, the present study reviews the data currently available on the molecular distribution of intestinal human amoeba in Iran.
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spelling doaj.art-c0706204ee43478ba7729c66c06fdfbe2022-12-21T19:31:53ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932012-09-01419Molecular Epidemiology of Human Intestinal Amoebas in IranH Hooshyar 0P Rostamkhani1M Rezaian2 Many microscopic-based epidemiological surveys on the prevalence of human intestinal pathogenic and non-pathogenic protozoa including intestinal amoeba performed in Iran show a high prevalence of human intestinal amoeba in different parts of Iran. Such epidemiological studies on amoebiasis are confusing, mainly due to recently appreciated distinction between the Entamoeba histolytica, E. dispar and E. moshkovskii. Differential diagnosis can be done by some methods such as PCR-based methods, monoclonal antibodies and the analysis of isoenzyme typing, however the molecular study of these protozoa in Iran is low. Based on molecular studies, it seems that E. dispar is predominant species especially in the central and northern areas of Iran and amoebiasis due to E. histolytica is a rare infection in the country. It is suggested that infection with E. moshkovskii may be common among Iranians. Considering the importance of molecular epidemiology of amoeba in Iran and also the current data, the present study reviews the data currently available on the molecular distribution of intestinal human amoeba in Iran.https://ijph.tums.ac.ir/index.php/ijph/article/view/2511AmoebaEntamoebaMolecular epidemiologyIran
spellingShingle H Hooshyar
P Rostamkhani
M Rezaian
Molecular Epidemiology of Human Intestinal Amoebas in Iran
Iranian Journal of Public Health
Amoeba
Entamoeba
Molecular epidemiology
Iran
title Molecular Epidemiology of Human Intestinal Amoebas in Iran
title_full Molecular Epidemiology of Human Intestinal Amoebas in Iran
title_fullStr Molecular Epidemiology of Human Intestinal Amoebas in Iran
title_full_unstemmed Molecular Epidemiology of Human Intestinal Amoebas in Iran
title_short Molecular Epidemiology of Human Intestinal Amoebas in Iran
title_sort molecular epidemiology of human intestinal amoebas in iran
topic Amoeba
Entamoeba
Molecular epidemiology
Iran
url https://ijph.tums.ac.ir/index.php/ijph/article/view/2511
work_keys_str_mv AT hhooshyar molecularepidemiologyofhumanintestinalamoebasiniran
AT prostamkhani molecularepidemiologyofhumanintestinalamoebasiniran
AT mrezaian molecularepidemiologyofhumanintestinalamoebasiniran