Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature
Abstract Purpose To describe imaging characteristics of severe macular complications occurring in glaucoma and discuss available treatments. Methods Retrospective case series of glaucomatous patients with macular retinoschisis (MR) and/or serous retinal detachment (SRD). Patients underwent a complet...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-023-03068-z |
| _version_ | 1797779003693596672 |
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| author | Hugo Lama Michel Pâques Emmanuelle Brasnu Jade Vu Céline Chaumette Bénédicte Dupas Christine Fardeau Ismaël Chehaibou Jean-François Rouland Guillaume Besombes Marc Labetoulle Antoine Labbé Antoine Rousseau |
| author_facet | Hugo Lama Michel Pâques Emmanuelle Brasnu Jade Vu Céline Chaumette Bénédicte Dupas Christine Fardeau Ismaël Chehaibou Jean-François Rouland Guillaume Besombes Marc Labetoulle Antoine Labbé Antoine Rousseau |
| author_sort | Hugo Lama |
| collection | DOAJ |
| description | Abstract Purpose To describe imaging characteristics of severe macular complications occurring in glaucoma and discuss available treatments. Methods Retrospective case series of glaucomatous patients with macular retinoschisis (MR) and/or serous retinal detachment (SRD). Patients underwent a complete ophthalmological examination and multimodal imaging including retinography, SD-OCT, fluorescein and indocyanine green angiography (FA & ICGA) and adaptive optics (AO). Results Ten eyes (8 patients) were included. Initial BCVA was 1.04 ± 1.12 logMAR and IOP was 24.0 ± 9.3mmHg. All eyes presented with MR while SRD was present in 5 eyes (5 patients), with a central macular thickness of 573 ± 152 μm. FA and ICGA allowed to exclude leakage in all cases. A focal lamina cribrosa defect (LCD) was found in four eyes (4 patients) using OCT, with AO providing en-face visualization of the defect in one eye. Outer retinal hole was present in 3 eyes (3 patients). No visual improvement or resolution of the macular retinoschisis was observed in eyes with medical or surgical IOP control (N = 9). Vitrectomy with internal membrane limiting peeling and gas tamponade was performed in one eye with good visual results. Conclusions Multimodal high-resolution imaging is essential to diagnose severe macular complications associated with advanced glaucoma. |
| first_indexed | 2024-03-12T23:25:30Z |
| format | Article |
| id | doaj.art-c0715209b36342b58497c4f31e6c35bc |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-03-12T23:25:30Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-c0715209b36342b58497c4f31e6c35bc2023-07-16T11:12:40ZengBMCBMC Ophthalmology1471-24152023-07-0123111110.1186/s12886-023-03068-zSevere macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literatureHugo Lama0Michel Pâques1Emmanuelle Brasnu2Jade Vu3Céline Chaumette4Bénédicte Dupas5Christine Fardeau6Ismaël Chehaibou7Jean-François Rouland8Guillaume Besombes9Marc Labetoulle10Antoine Labbé11Antoine Rousseau12Department of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris SaclayDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU ForesightDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU ForesightDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris SaclayDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU ForesightDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris SaclayDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris SaclayOphtalmopôle Cochin, APHPDepartment of Ophthalmology, Hôpital Claude Huriez, CHRUDepartment of Ophthalmology, Hôpital Claude Huriez, CHRUDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris SaclayDepartment of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU ForesightDepartment of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris SaclayAbstract Purpose To describe imaging characteristics of severe macular complications occurring in glaucoma and discuss available treatments. Methods Retrospective case series of glaucomatous patients with macular retinoschisis (MR) and/or serous retinal detachment (SRD). Patients underwent a complete ophthalmological examination and multimodal imaging including retinography, SD-OCT, fluorescein and indocyanine green angiography (FA & ICGA) and adaptive optics (AO). Results Ten eyes (8 patients) were included. Initial BCVA was 1.04 ± 1.12 logMAR and IOP was 24.0 ± 9.3mmHg. All eyes presented with MR while SRD was present in 5 eyes (5 patients), with a central macular thickness of 573 ± 152 μm. FA and ICGA allowed to exclude leakage in all cases. A focal lamina cribrosa defect (LCD) was found in four eyes (4 patients) using OCT, with AO providing en-face visualization of the defect in one eye. Outer retinal hole was present in 3 eyes (3 patients). No visual improvement or resolution of the macular retinoschisis was observed in eyes with medical or surgical IOP control (N = 9). Vitrectomy with internal membrane limiting peeling and gas tamponade was performed in one eye with good visual results. Conclusions Multimodal high-resolution imaging is essential to diagnose severe macular complications associated with advanced glaucoma.https://doi.org/10.1186/s12886-023-03068-zAdaptive opticsGlaucomaHigh-resolution imagingMacular edemaRetinoschisisSerous retinal detachment |
| spellingShingle | Hugo Lama Michel Pâques Emmanuelle Brasnu Jade Vu Céline Chaumette Bénédicte Dupas Christine Fardeau Ismaël Chehaibou Jean-François Rouland Guillaume Besombes Marc Labetoulle Antoine Labbé Antoine Rousseau Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature BMC Ophthalmology Adaptive optics Glaucoma High-resolution imaging Macular edema Retinoschisis Serous retinal detachment |
| title | Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature |
| title_full | Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature |
| title_fullStr | Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature |
| title_full_unstemmed | Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature |
| title_short | Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature |
| title_sort | severe macular complications in glaucoma high resolution multimodal imaging characteristics and review of the literature |
| topic | Adaptive optics Glaucoma High-resolution imaging Macular edema Retinoschisis Serous retinal detachment |
| url | https://doi.org/10.1186/s12886-023-03068-z |
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